| Red flower of compositae safflower Carthamus tinctorius l. tubular corolla, for annual or biennial herb, in most parts of our country have distribution and cultivation.Safflower mainly contain naphthoquinone, flavonoids, coumarins, organic acids, generation of steroids and other compounds and amino acids, organic acids, protease, saccharase, fructose, glucose and other substances, invigorate the circulation of menstruation, loose silt pain, used to amenorrhea, dysmenorrhea, lochia not, remove lump a lump in the abdomen, falling injury, ulcers sore and other functions, has the very good development prospects.Safflower pharmacological effects is very extensive, low toxicity, in treatment of coronary heart disease, cerebral thrombosis, cerebral atherosclerosis, hypertension and other diseases of the cardiovascular system achievements has been widely confirmed.Safflower has now been developed into a variety of single and compound preparation, injection, capsule, tablet, granules and other dosage forms, but the overall quality is still a certain deficiencies.Many red flower of current quality standard is not clear, should strengthen and perfect the safflower formulations of current quality standard.More importantly should strengthen and control the quality of the raw material medicine safflower, from safflower growing, harvesting, processing, transportation and storage process strictly control the quality of the red flowers, only in this way can help the industrialization development of safflower, constantly improve the quality and market competitiveness of China’s traditional Chinese medicine.At present domestic to safflower medicines quality standard is not very perfect, only to strengthen the research of its quality standard, the quality standards for standardization, can better to study, development and utilization.In this paper, the red flower medicine quality standard related content is studied.The concrete research content is as follows:1. To collect 30 different sources of safflower medicines quality standard study, the moisture, total ash, acid insoluble ash content, extract the test items such as determination of absorbance value 0.1403 ~0.6960;Total ash and acid insoluble ash content 5.70% ~39.30%, 0.20%~29.7%, extract content 6.57%~6.57%;The results look at hetian red flowers points and acid insoluble ash content is higher, low absorbance.2. The collected from the national germplasm repository of 30 different varieties of safflower medicines quality standard study, the properties, appearance, clarity, fragmentation, heavy metals(lead, arsenic, mercury, cadmium, copper and other quality control items tested;For each batch of safflower medicines of heavy metals(lead, arsenic, mercury, cadmium, copper) for testing, the study found the xinjiang safflower in hotan area total ash and acid insoluble ash content exceeds bid, heavy metals arsenic content is higher;3. High performance liquid chromatography(HPLC) method for hydroxyl groups in safflower safflower yellow pigment, rhizoma kaempferiae element composition such as A studied the content determination;The results look of hydroxy safflower yellow pigment in hotan area A and galanga resurrectionlily element content is low, ili region is higher;4. According to the main component content in safflower data quality evaluation system is established;Different production areas, quality differences and market circulation safflower, sand exist in the market circulation of safflower impurities. |