| Objective:Observation of coronary heart disease patients with diabetes mellitus coronary artery intervention(PCI) after the change of lipid peroxidation damage index, and progress of coronary artery lesions.Methods:Choice of 38 patients with coronary heart disease(group A) and 42 cases of coronary heart disease combined with diabetes(group B) for PCI, respectively in the interventional treatment immediately before and after the treatment, 30 min, 1 h, 24 h and 7 d blood determination of malondialdehyde(MDA) and superoxide dismutase(SOD) levels, and dynamic follow-up of PCI postoperative coronary artery disease.Results:(1). Two groups of postoperative patients with the level of MDA and SOD was compared with preoperative have obvious changes, lipid peroxide index change obviously, but this kind of change is more obvious in group B, and 7 dayspostoperatively, still have obvious changes in group B, group A is close to preoperative levels.(2)12 months follow-up found that group B patients with restenosis, death,cardiovascular events were significantly higher in group A(P < 0.05), the incidence of stroke has no obvious difference(P > 0.05), chi square values were 4.20, 4.21,5.17, 0.30, 22.33.Conclusions:Coronary heart disease patients with diabetes mellitus PCI postoperative changes of lipid peroxidation damage index and duration is long, diabetes can promote the damage process. |
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