Study On The Correlation Between The TCM Syndrome Type And The HRCT Quantitative Of The Patients With Lung Distension

Objective:To investigate the characteristics and differences of chronic obstructive pulmonary disease(COPD) in patients with Fei Qi deficiency syndromeand syndrome of phlegmheat obstructing lung,discussion of two types of lung inflation syndrome type and airway remodeling(ARM) high resolution computed tomography(HRCT) quantitative correlation,and to provide evidence for clinical diagnosis and treatment, treatment and efficacy evaluation.Methods:The subjects were selectedfrom Aug 2013 to 2014 Nov by Traditional Chinese Medicine(TCM) Hospital of Yunnan Province, normal people as control group were selected the same period in physical examination center.Total 92 cases, syndrome differentiation of chronic obstructive pulmonary disease(COPD) is Fei Qi deficiency syndrome in 45 patients,syndromeof phlegmheat obstructing lungin 47 cases, and 40 normalsubjects.HRCTwere performed in the subjects,observed lung lesions changes in Medical Imaging.We used the thoracic volume complex acquirement andreconstruction(VCAR) software to analyze the Wall thickness(WT), inner diameter(Din), wall area(WA),percentage of wall area(WA%) of upper lobe apical segmental and sub-segmental bronchias well as lower lobe posterior basal segmental and sub-segmentalbronchi of right and left lung, and then the results were compared and analyzed, to explore the characteristics and differences of airway remodeling in patients with different types of COPD.Results:1. Airway remodeling of all COPD patients were existed in segmental and sub-segmental bronchi,we observeddifferent degrees of bronchial wall thickening and luminal narrowingby HRCT examination.2. Airway remodeling of Fei Qi deficiency syndrome patients existed mainly in segmental bronchi, and airway remodeling of syndromeof phlegmheat obstructing lungpatients was more apparent in sub-segmentalbronchi,the difference was statistically significant(P<0.05). Airway remodelingis displayed as the WT increase, narrowing the din, WA% increase, but WA no changesignificantly.3.Airway remodeling of syndromeof phlegmheat obstructing lung patients was more apparent in segmental and sub-segmentalbronchi.Airway remodelingis displayed as the WT increase, narrowing the din, WA% increase, but WA no changesignificantly.4.Bronchial WTincreased grading and emphysema signs are statistical differencewith Fei Qi deficiency syndrome and syndromeof phlegmheat obstructing lung.WTincreased withsyndromeof phlegmheat obstructing lungwere obvious.COPD Patients with Fei Qi Deficiency signs of emphysema, compared with syndromeof phlegmheat obstructing lungwere significantly. The differences of the two signs was statistically significant(P<0.05).Exudative lesions in the lung phlegm obstruct the lung are more common.Conclusions:Airway remodeling of Fei Qi deficiency syndrome and syndromeof phlegmheat obstructing lung were existed in segmental and sub-segmental bronchi.Airway remodeling of Fei Qi deficiency syndrome patients existed mainly in segmental bronchi.Airway remodeling of syndromeof phlegmheat obstructing lungpatients were existed mainlyin sub-segmental bronchi.Bronchial WTincreased grading and emphysema signs are statistical differencewith Fei Qi deficiency syndrome and syndromeof phlegmheat obstructing lung.WTincreased withsyndromeof phlegmheat obstructing lungwere obvious.Signs of emphysema with Fei Qi deficiency syndrome were obvious.Exudative lesions in the lung phlegm obstruct the lung are more common.The differences and correlations of COPD with different TCM syndromes in lung parenchyma and airway remodeling can reveal individual differences in the characteristics of COPD’s disease in different degrees, and help to reveal the essence and pathogenesis of COPD. HRCT can effectively evaluate the changes and airwayremodeling of COPD patients.