The Characteristic Research Of Chronic Atrophic Gastritis Precancerous Lesions Related To "Phlegm" "Wet" Syndrome Based On The Theory Of Syndrome Factor

Objective:Precancerous lesions of chronic atrophic gastritis "phlegm" "wet" symptoms relevant evidence element distribution, gastric mucosa pathological manifestations and Hp infection, chronic atrophic gastritis and the precancerous lesions "phlegm" "wet" symptoms relevant evidence distribution of contrast, analysis of the "wet" and "phlegm" Precancerous lesions of chronic atrophic gastritis correlation, for clinical evidence-based medicine provides.Methods:1.Using questionnaire survey and case-control method, taking 45 cases of treatment by electronic endoscopy and biopsy clear chronic atrophic gastritis of precancerous lesions in the XX Hospital, and has clinical symptoms, the patient is satisfied that compliance with discharge standards, as observed object, in addition to collect 45 cases of chronic atrophic gastritis precancerous lesions of non-patients in the control group.2. According to Professor Zhu Wenfeng proposed the syndrome differentiation principle, will be collected four diagnostic information, to calculate the integral of syndrome, syndrome elements of each case each, will more than 100 points to determine the symptom factors for the syndrome diagnosis was established, the clinical appearance and syndrome respectively in different syndromes, such as phlegm and wet both respectively in sputum and wet syndrome. According to the "phlegm" and "wet" syndrome diagnostic set or not from the observation group, respectively (precancerous lesions of chronic atrophic gastritis) and control group (chronic non atrophic gastritis precancerous lesions) extracted related cases in the observation group, analysis of "phlegm" " wet" syndrome, syndrome distribution, gastric mucosal pathology, Hp infection and "phlegm" "wet" correlation, and the control group and the phlegm dampness syndrome were compared, discussion and analysis of "phlegm" "wet" and precancerous lesions of chronic atrophic gastritis lesion development correlation.Results:1. In the precancerous lesions of chronic atrophic gastritis, "phlegm, wet" syndrome cases respectively accounted for 77.78% and 82.22%, the distribution is different in different ages, with the middle-aged (40～60), the average age groups is higher than that of "phlegm" syndrome related to dampness group.2. Chronic atrophic gastritis and precancerous lesions of "phlegm" and "wet" syndrome related and syndrome element distribution characteristics:(1) "phlegm" syndrome diagnosis was established, the "wet" syndrome diagnosis is also established; (2) and clip disease syndrome factor relates to the stomach, spleen liver, kidney, intestine, small intestine, stomach, spleen, liver, and disease syndrome known as qi stagnation, Qi deficiency, Yang deficiency, blood stasis, heat, indigestion, yin deficiency, blood deficiency, qi stagnation, Qi deficiency, Yang deficiency; (3) disease of qi deficiency and yang deficiency, yin deficiency and blood stasis, distribution between Chronic atrophic gastritis and precancerous lesions and Chronic atrophic gastritis and precancerous lesions "phlegm" syndrome has difference (P<0.05).3. Chronic atrophic gastritis precancerous lesions and non cancer precursor lesions of "phlegm" "wet" card and card folder distribution comparison:(1) Chronic atrophic gastritis precancerous lesions "phlegm" syndrome and blood stasis syndrome with kidney-diagnosis was greater than the probability of Chronic atrophic gastritis (P<0.05); (2) Chronic atrophic gastritis and precancerous lesions "wet" card and clip syndrome of spleen, liver, kidney, Yang deficiency, heat, blood stasis, yin deficiency diagnosis was greater than the probability of Chronic atrophic gastritis (P<0.05).4. Chronic atrophic gastritis and precancerous lesions of "phlegm" "wet" syndromes and Hp infection:"phlegm" "wet" card related cases of Hp infection and non phlegm wet syndrome related cases of Hp infection have difference (P<0.05), "phlegm" "wet" related cases the positive rate was higher than the non phlegm dampness related cases.5. Chronic atrophic gastritis and precancerous lesions of "phlegm" and "wet" syndrome and gastric mucosa pathological changes:correlation between gastric mucosa pathological changes of Chronic atrophic gastritis and precancerous lesions distribution related cases in phlegm syndrome cases and non phlegm syndrome has the difference between (P<0.05), the phlegm syndrome the higher the points, the more severe lesions; and distribution between dampness and non related "wet" card has no difference (P>0.05).Conclusion:1. Chronic atrophic gastritis and precancerous lesions of the origin and development of "phlegm, wet" is closely related with "phlegm" will be "wet", "phlegm" syndrome in the "wet" card developed on the basis of development, from Chronic atrophic gastritis to precancerous lesions, the pathological products by the end of the "wet" of "phlegm".2. Chronic atrophic gastritis and precancerous lesions of "phlegm, wet" related to disease, stomach, spleen, liver, intestine, kidney disease, and qi stagnation and blood stasis, Qi deficiency, indigestion, and yang deficiency.3. Chronic atrophic gastritis and precancerous lesions of "phlegm, wet" the infection rate of Hp is relatively higher, the severity of gastric mucosa with phlegm syndrome severity is serious.4. That phlegm is the precancerous lesions of chronic atrophic gastritis is an important pathological product, especially kidney yang deficiency, blood stasis and non precancerous lesions are different, therefore we should pay attention in the treatment of phlegm stasis stagnation, spleen and stomach regulating the function of liver and kidney.