Primary Hepatocellular Carcinoma Radical Initiated Adjuvant Tace Clinical Analysis

Objective:In this paper, through a retrospective analysis and comparison of primary liver cancer resection and postoperative interventional chemotherapy through hepatic artery embolization (TACE). The effect of intervention scheme on primary liver cancer, comprehensive analysis of factors affecting the prognosis. Aims to explore whether routine postoperative liver cancer patients with TACE intervention, such as to improve the effect of the treatment of liver cancer, and provide certain theoretical basis for the evaluation of prognosis.Method:We through a retrospective analysis of 170 patients underwent resection of the liver cancer after TACE therapy and simple resection of liver cancer patients, with conventional statistical its general situation, survival rate, the influence factors of screening. Through the log-rank test grouping variable between survival curve, risk of Cox model analysis influence line liver resection and postoperative survival of interventional therapy with conventional factors.Result:In the study group with TACE median survival time after liver resection for 58 months, including 1,2,3,5 years of cumulative survival rates were 86.3%,81.3%,72.8% and 47.2% respectively. Median disease-free survival time was 13 months, including 1,2,3,5 years of recurrence rates were 50.8%, 70.5%,72.1% and 82.0% respectively. And pure liver cancer resection group median survival time was 54 months, including 1,2,3,5 years of cumulative survival rates were 82.1%,68.5%,60.7% and 27.0% respectively. Median disease-free survival was 11 months, including 1,2,3,5 years of recurrence rates were51.8%,66.1%,75.0% and 80.4% respectively. By Cox regression analysis of multiple factors showed that intrahepatic tumor metastasis, preoperative AFP value is has a significant influence on overall survival time. And intrahepatic tumor metastasis, tumor diameter, the microscopic tumor emboli are for disease-free survival time has significant influence factors.Conclusion:Patients with the eradicative resection of hepatocellular carcinoma treated with TACE after can prolong overall survival time and prolong overall survival time of 2 years.For preoperative AFP 400 ng/ml, or big diameter (5 cm or higher) of liver cancer patients, Patients with the eradicative resection of hepatocellular carcinoma treated with TACE after can prolong overall survival time. Has spread to the liver cancer patients with preoperative and postoperative HCC treatment with TACE is meaningful. And can prolong the patient’s disease-free survival and overall survival time, improve patient surial.