A Prospective Study Of Ultrasound Assessment Of Healthy Volunteers’ Liquid Gastric Emptying

Objectives: To observe the gastric emptying time of different kinds of liquid and to explore the main determinants of liquid gastric emptying.Methods: Part one: elect 10 healthy volunteers, the male to female ratio was 1:1. Inclusion criteria were age between 16~80y,ASA physical status I to II,BMI index between 19~25kg/m2. Meanwhile, the volunteers who were pregnant, diabetes and who had diseases of the digestive system should be excluded. Each volunteer should drink 200 ml of four different kinds of liquids: water, tea, milk and 10% glucose injection. After liguid ingestion, the subject was kept in a right arm recumbent position at a 45 °angle and got the image of cross-sectional area. Record the anteroposterior and craniocaudal of the point of pre-test, drink liquid immediately, drink in 90 minutes every 10 minutes. Record the gastric emptying time. Calculate the cross-sectional area and gastric volume by the formula. Part two: Using the same criteria to elect 6 more healthy volunteers. Each volunteer should drink 200 ml of five different kinds liquids: water, 10% glucose injection, pure milk and water mixture, 10% glucose injection and 50% glucose injection mixture, pure milk mixture(0, about 80 kcal, about 120kcal). Using the same scan strategy and record the anteroposterior and craniocaudal of the point of pre-test, drink in 60 minutes every 10 minutes and calculate the cross-sectional area and gastric volume by the formula.Results: Part one: the mean gastric emptying time of the W group(29.3±3.1min) was shorter than the T group(36.9±3.8min), the 10%G group(66.3±2.7min) and the M group(76.8±4.5min)(P <0.05). In the 70 minutes after liquid ingestion, the mean cross-sectional area and the mean gastric volume of the M group were larger than other three groups(P<0.05). In the last 20 minutes, the mean cross-sectional area and the mean gastric volume of four groups were no difference(P>0.05). In the 60 minutes after liquid ingestion, the mean cross-sectional area and the mean gastric volume of the 10%G group were larger than the W group and the T group(P<0.05). In the last 30 minutes, the mean cross-sectional area and the mean gastric volume of the 10%G group were no difference with the W group and the T group(P>0.05). In the 30 minutes after liquid ingestion, the mean cross-sectional area and the mean gastric volume of the T group were larger than the W group(P<0.05). In the last 60 minutes, the mean cross-sectional area and the mean gastric volume of the T group were no difference with the T group(P>0.05).Part two : In the 60 minutes after liquid ingestion, the mean cross-sectional area and the mean gastric volume of the 10%G + 50%G group were larger than the 10%G group(P<0.05), the mean cross-sectional area and the mean gastric volume of the M group were larger than the M+W group(P<0.05). The mean cross-sectional area and the mean gastric volume of the 10%G + 50%G group and the M group were no difference(P>0.05). There were also no difference between the10%G group and the M+W group(P>0.05). The mean cross-sectional area and the mean gastric volume of the W group were smaller than others in 60 minutes(P<0.05).Conclusions: 1. The gastric emptying time of 200 ml of 4 kinds of liquids are pure milk longer than 10% glucose injection, than tea, than water. 2. Liquid gastric emptying depends chiefly on the total caloric, not the component and the property.