The Characteristics Of Depressive Emotions In Late Pregnancy And Neurobehavioural Development Of Neonates And The Correlational Study

Fetal and neonatal period is extremely crucial for brain development, which is called critical period in medical field. In this period, the negatively physical,psychological and social factors of mother and the negatively genetic, pathological,nutritious and environmental factors of child contribute to the abnormality of morphology and function of brain. The abnormally neurobehavioural development is one of the most common consequences, mainly manifesting the incapability of coarse and refined motions, perception, language and interpersonal functions. By comprehending the results of studies at home and abroad, we found that researchers mainly focus on the effects of psychology of mother on the quality of life, body weight at birth, dysmorphia and neonatal blood pressure of child, and on the influence of postpartum depression, pregnancy trauma, negative life events and stress of mother on the neurobehavioural development, but rarely on the correlation between depressive emotions in late pregnancy and characteristics of neurobehavioural development of neonates. Our research firstly examined the demographic characteristics of depressive emotions in late pregnancy and then identified the influential factors that may cause depression. According to the identified factors, we designed an intervention program for enhancing psychological health of pregnant and puerperant women. Next, we explored the relationship between the incidence of abnormally neurobehavioural development and the gender of child, way of delivery and body weight at birth. Lastly, we provided important factors for screening high-risk neonates and designed recovery training programs, which has a great value in clinical field.Subject and methods:We used formal questionnaire method. With the guidance of trained doctors andnurses, 251 pregnant women with pregnancy over 28 weeks were recruited as participants, and were surveyed with structure questionnaires on personal information,Edinburgh Postnatal Depression Scale(EPDS) and Negative Cognition Bias Scale(NCPBS). We longitudinally observed neonates at hospital and ultimately collected the scores in INFANIB of 1334 neonates. We identified 84 neonates who were the children of previously surveyed women from the 1334 neonates.We analyzed the data with Excel 2007 and SPSS 13.0. The statistical methods include descriptive analysis, chi-square test, t test, one-way ANOVA and Pearson correlation. All p values were below 0.05. Analyzed the characteristics of depressive emotions in late pregnancy and neurobehavioural development of neonates and their correlation. Designed psychological health recovery training and intervention programs for pregnant and puerperant women, and established regulations of screening and recovery training for high-risk neonates.Results:(1) The incidence rate of depressive emotions in late pregnancy was 12.35%. The depressive emotions in late pregnancy were related to the relationship between mother-in-law and daughter-in-law, family income and educational level of the pregnant women. Depressive emotions in high or low educational high level of the pregnant women was significantly higher middle educational high level of the pregnant women.(2) The incidence rate of negative cognition bias in late pregnancy was 30.89%.Scores of Edinburgh Postnatal Depression Scale(EPDS) were significantly relation to scores of Negative Cognition Bias Scale(NCPBS). The late pregnant women with negative cognition had three components of negative cognitive processing bias:negative memory bias,negative interpretation bias and negative rumination bias.(3) In our sample, 44.80% neonates would or had been had neurobehavioural development. And there were more females than males.(4) There were no significant differences compared Scores of Edinburgh Postnatal Depression Scale(EPDS) with scores in INFANIB. Negative cognition bias negatively correlated with scores in INFANIB. Compared to normal population, mother with negative attention bias and rumination bias had higher possibility to deliver neonates having neurobehavioural development.(5) Compared to pregnant women with good nutrition, those who had poor nutrition had higher likelihood to deliver neonates having abnormal neurobehaviouraldevelopment.Conclusion:The incidence rate of depressive emotions in late pregnancy and neonates neurobehavioural development were high. The depressive emotions in late pregnancy were related to the relationship between mother-in-law and daughter-in-law, family income, educational level of the pregnant women and negative cognition bias. Negative cognition bias negatively correlated with scores in INFANIB. Pregnant women with nutrition had higher likelihood to deliver neonates abnormal neurobehavioural development.