| Objective: To evaluate the laparoscopic ovarian endometriosis(chocolate cyst) affect cystectomy on ovarian reserve function, other destination have to find markers to assess the diagnostic value of ovarian reserve, designed to preoperative ovarian reserve assessment and postoperative recovery and assessment of ovarian reserve testing to provide the most valuable indicators..Methods: Select December 2014- August 2015 visit to the First Affiliated Hospital of Medical College, Shihezi University Obstetrics and Gynecology ovarian cysts by laparoscopic ovarian cyst removed in the treatment of cases of 112 cases, all cases included in the study in postoperative pathology diagnosis were diagnosed with ovarian endometriosis, ovarian simple cyst, mature teratoma, serous cyst,mucinous cysts, corpus luteum cyst, benign ovarian cysts. 60 patients with ovarian endometriosis patients as the study group, other benign ovarian 52 patients as a control group, the study group and control group were further divided according to age group 16 to 34 years, 35 to 45 age group. All patients were preoperatively collected venous blood 5 mL,count the outcome of CA125; the patients in the study group after injection of Gonadotropin releasing hormone analogue treatment and then at the end of the first day of Menstruation collected venous blood 5 mL, in the control group after the first day of Menstruation venous blood collected 5 mL. By ELISA respectively before and after surgery to detect serum anti-Mullerian hormone, inhibin B level, evaluate laparoscopic ovarian endometriosis cyst removed effect of postoperative ovarian reserve.Results:1. Ovarian endometriosis cyst excision, under the control group were 52 patients underwent laparoscopic excision of ovarian cysts, another group is under study were 60 patients underwent laparoscopic the differences of two groups of patients in age, body mass index, ovarian cyst the size of the group were not statistically significant(P > 0.05).2. Unilateral ovarian endometriosis patients with preoperative serum levels of AMH expression and INHB for expression level in patients with bilateral ovarian cysts endometrium comparison, unilateral ovarian endometriosis group preoperative serum AMH levels were higher and INHB ovaries endometriosis patients, no significant difference(P > 0.05).3. All patients included in the study were divided into four groups: 20-24 years of age group, 25-29 age group, 30-34 age group, 35-45 year-old group. Comparison of serum AMH and INHB of four groups,the serum of AMH, INHB was negatively correlated, the difference was statistically significant(P<0.05).4. Study group of 60 patients were divided into two groups according to age: <35 years of 22 cases,38 cases of ≥35 years old group, the control group 52 patients were divided into two groups: <27 cases of35-year-old group, ≥35 years of age group contained 25 examples. Study group <35 years old group, the former group of patients ≥35 years of serum AMH, INHB expression levels were lower than the control group <35 years group, the former group of patients ≥35 years are lower in the serum AMH, the expression level of INHB. Study group <35 years old group, ≥35 years old group postoperative serumAMH, INHB expression levels were lower than the control group <35 years old group, the expression levels ≥35 years of postoperative serum INHB.5. By postoperative ipsilateral ovary AFC and ovarian volume were compared, one ovary clever capsule ipsilateral ovary patients were less than the average of the normal side ovary, it showed a significant difference(P < 0.05).6.The study group serum level of CA125 before operation has no relationship with AMH and INHB.Conclusion:1. Laparoscopic surgery ovarian cyst removed to some extent affect ovarian reserve, with increasing age, the greater the likelihood of the occurrence of postoperative ovarian reserve reduction.2. Whether the patients underwent unilateral or bilateral ovarian cyst removed surgery affect ovarian reserve is not significant.3. AMH and INHB can reflect the changes of benign ovarian cysts ovarian reserve,AMH is more diagnostic value than INHB..4. AFC and ovarian volume can also be used as an indicator of aid in the assessment of ovarian ovarian function5. Ovarian endometriosis preoperative CA125 and AMH, INHB levels were not correlated... |
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