Retrospective Analysis Of 163 Radical Resection Cases Of Hepatic Alveolar Echinococcosis

Objective: To study the therapeutic effort in patients who received liver radical resection for hepatic alveolar echinococcosis.Methods: The clinical data of patients who received radical hepatectomy for hepatic alveolar echinococcosis carried out in Affiliated Hospital of Qinghai University were analyzed retrospectively.Results: Between January 2013 to June 2015, 163 patients with hepatic alveol ar echinococcosis received radical hepatectomy. The mean time of radical surge ry was(3.1±1.2) hours and the mean intraoperative blood loss was(763±498) millilitre. The median time of patients with intraperitoneal drainage tube after t he operation was 6 days, and 11 patients with T-drainage tube were removed i n one month. The mean time of flatulence afetr operation was(2.1±0.8) days, and postoperative feeding time was(2.7±1.1) days. The mean duration of postoperative hospitalization was(7.9±3.4) days. After surgery, 8 patients developed complications, including 5 associated with bile leakage, 1 with surgical site in fection, and 2 with ascites. The changes of liver function were statistically sig nificant about before and after the surgery(P<0.001). The group of infiltation r esection range about 0.5cm≤W<1.0cm and W≥1.0cm have significant differen ce in operation time(P=0.011) and intraoperative blood loss(P=0.001). Two gr oups exist obvious difference between postoperative 3 days and preoperative 1 day in ALT, AST, TBIL and ALB(*P<0.05). Comparative analysis between the two groups before and after treatment of liver function, postoperative 3 days’ AST and ALT exist obvious differences(ΔP<0.05). Death or recurrent echinoc occosis was not reported from any patient over the 1-6 months of telephone o r outpatient follow-up.Conclusions: Radical surgery as a bubble type liver echinococcosis is an effec tive treatment, resection of lesions around 0.5cm above the normal liver tissue can avoid damage the liver structure, shorten the operation time, reduce intrao perative bleeding, reduce the postoperative liver function damage, short-term follow-up found no cases of recurrence. Fully grasp the liver blood flow control technology, surgical anatomy of the liver, portal vein reconstruction, bile duct reconstruction techniques. Through radical resection and good nursing care and postoperative complications of active treatment, can cure patients with echinoc occosis.