Research On Logic Operation Based On Dynamic DNA Self-assembly

In recent years,DNA as a carrier of genetic material,which has inherited a huge task of information genetics.The development of DNA nanotechnology has become one of the research hotspots in the field of biological information processing.The model construction of DNA nanostructures and the design of nanologic logic circuits are two of the most urgent problems to be solved in the current control field.Through the research on the theory and application of DNA circuit self-assembly model and logic circuit design methods for chain replacement,there is a solid theoretical support provided and some practical methods created by DNA computing research applied in biological information.In this paper,the six-armed DNA sub-tile molecular tile model and the strand replacement technology are used as research objects.Through the bottom-up self-assembly theory and strand replacement technology,the operation of the XOR and OR nano-logic are discussed,and the nanotechnology is used.The logic circuit make these practical problems solved.The main contents are as follows:Aiming at the instability of the previous four-arm molecular tile model structure,six kinds of DNA sub-tile tile single-chain structures with different lengths were designed,and six arms were constructed based on the sticky-end complementarity of single-chain molecular tile sequences.A six-arm molecular tile model structure was constructed according to the principle of complementary end-to-end matching,and the XOR and XNOR logic operations were designed by using the structure of the six-armed DNA sub-tile model.Based on these two operations,the operation was performed again.The design of nano-graphics,namely the construction of the Chinese map model structure based on XOR operations and the construction of the Asian map model structure based on the same OR operation,this provides a good theoretical basis for future applications in biological computers.The fire alarm system was designed for the inaccurate judgment of traditional fire alarm devices and the possibility of false alarms.Smoke alarms,temperature sensors,light sensors,and hand-held devices were used as four types of fire detection signals.The output results are represented by binary numbers.The output simulation results performed using the DSD software.The simulation results show that the alarm circuit device design has high reliability.Aiming at the problems of large size,inaccurate calculation and slow operation speed of traditional computers,the odd judgment circuit and the matrix vector multiplication logiccircuit are designed.The feasibility of the entire circuit design can be programmed and simulated by DSD software.Through the compilation of the program of the computing device,the input and output simulation results are given.According to the simulation results,it effectively proves the effectiveness of the circuit design.It shows that it is feasible to use the method of DNA strand replacement to realize more complex logical operations,promote the development of DNA biological computers,and hopefully in the design of more complex logic circuits.This article explores the issue of biological computations in both DNA self-assembly and strand replacement.It explores the application of DNA nanomaterials in logic computations in biological computers and the design and simulation of integrated circuits.It further expands the construction of nanoscale model structures and nanocircuits.The design ideas have a certain theoretical guiding significance for the development of biological computers.