Correlation Analysis Of The Nutritional Status And Quality Of Life Of Patients With Digestive Tract Cancer

Objetive: Through the application of patients with self rating subjective global nutritional assessment table(patient-generated subjective global assessment(PG-SGA)and tumor patients quality of life(QOL)table EORTC QLQ-C30V3.0 Chinese version of hospitalized in Xingtai City People's Hospital of malignant tumor of digestive tract in patients with nutritional status and quality of life assessment survey.the purpose of the study was to understand the nutritional status of patients with digestive tract cancer in Xingtai People's Hospital,and to explore the correlation between nutritional status and quality of life,so as to provide reference for clinical nutrition support treatment.Methods:1 Subjective global assessment(SGA)is employed in this study.Anthropometric and laboratory testing method for September 2015 to January 2016 in Xingtai City People's Hospital of gastrointestinal tumor surgery,hospital oncology and thoracic surgery and pathological diagnosis for patients with malignant tumor of digestive tract of investigation and assessment of nutritional status,the quality of life was assessed using the QLQ-C30V3.0 EORTC Chinese version of the cancer patients,and all the patients met the inclusion criteria.Specific content includes the digestive tract malignant tumor patients with laboratory test,body mass index,eating,symptoms,activity ability and physical function,disease,relationship between nutritional status and quality of life by functional area evaluated.2 Data collection and analysisTo investigate the way of face-to-face interviews,the investigators through a unified training,to ensure that the questionnaire in the investigator's accurate description of the completion of the contents.Data collection after finishing,analysis and description of the data,using SPSS analysis,qualitative data using frequency description and quantitative data using mean and standard difference is described;influencing factors analysis using multiple linear regression.Results:1 The study of selected digestive tract malignant tumor patient issued 110 questionnaires,101 valid questionnaires were recovered and efficiency into 91.82%,of which 73 cases of male(72.3%),female 28 cases(27.7%);upper digestive tract malignant tumors,including esophageal cancer,gastric cancer)of 71 patients(70.3%),lower digestive tract malignant tumors(including colon cancer,rectum)of 28 patients with(27.7%)had two or more of the tumor patients in 2 cases(2.0%).2 According to the PG-SGA score results of patients for assessment of nutritional status,investigation of patients with good nutrition in 28 cases(27.7%),mild / moderate malnutrition in 52 cases(51.5%),severe nutritional bad in 21 cases(20.8%)and the Karnofsky score of the three groups of patients with average value is 80.1 points,good nutrition were 92.86 points,mild / moderate malnutrition patients 80.77 points,patients with severe malnutrition 61.43 points,the difference is statistically significant(P <0.05),pairwise comparison of the good nutrition group of patients with Pneumocystis score higher than the other two groups.3 Well nourished patients,mild/moderate malnutrition patients and severe nutrient poor patients with three groups of patients with age distribution were compared,the difference is statistically significant(P <0.001)and good nutrition in patients with average age of less than other two groups.Compared three groups of patients with BMI,severe malnutrition patients,mild / moderate malnutrition in patients with good nutrition in patients with BMI are different,the difference is statistically significant(P <0.05),mild to moderate malnutrition patients,severe malnutrition in patients with BMI significantly below the well nourished patients.4 Three groups of patients with analysis of hospitalization expenses and hospitalization time,good nutrition in patients with the average length of stay is 9.96 days,the average hospitalization cost $13926.74,mild/moderate malnutrition in patients with the average length of stay is 12.35 days,the average hospitalization cost $20284.32,severe malnutrition in patients with average hospitalization time 16.43 days,the average hospitalization cost $28699.45.Among the three groups hospitalization time,cost of hospitalization were similar were with statistical significance(P <0.05),severe malnutrition in patients with hospital stay,hospital costs were significantly higher than those of well nourished patients,although higher than mild / moderate malnutrition patients,but no statistical significance.5 Parts of nutritional status were significantly influence the pathogenesis of malignant tumors in patients with upper digestive tract malignant tumor patients with good nutrition,light/moderate malnutrition and severe malnutrition were accounted for 6.9%,51.4% and 41.7%.Digestive road in patients with malignant tumor of good nutrition,light/moderate malnutrition and severe malnutrition were 44.8%,48.3% and 6.9%.Digestion tract malignant tumors of lower digestive tract malignant tumor more easily malnutrition(?2=24.576,P <0.001).6 Three groups of patients with mid upper arm week diameter(MAC),upper arm muscle circumference diameter(MAMC),the difference was not statistically significant(P >0.05),among the three groups of triceps skinfold(TSF),right leg week diameter,left leg week diameter,non dominant hand grip strength exist significant difference(P <0.05),well nourished patients with triceps skinfold thickness(TSF),right leg week diameter,left leg week diameter is significantly higher than the mild / moderate malnutrition patients and severe nutritional patients with poor,well nourished patients,mild/moderate malnutrition in patients with non profit grip strength was significantly higher than that of severe nutrient poor patients.7 Three groups of laboratory indicators analysis,good nutrition group,mild / moderate malnutrition group and severe nutrient poor groups of total bilirubin,direct bilirubin,creatinine,blood urea nitrogen(BUN),AST,alt,white cell differences had no statistical significance(P >0.05),among the three groups in total protein level,serum albumin,hemoglobin,red blood cell difference has statistical significance(P <0.05),good nutrition in patients with total protein,serum albumin,red blood cells were higher than mild / moderate malnutrition patients,mild/moderate malnutrition in patients with serum albumin is higher than that of severe nutrition in patients with poor and good nutrition in patients with hemoglobin is higher than that of patients with severe malnutrition.8 Social function and general health scores of nutritional status with negative to significantly affect social function,the higher total scores for the well-being and nutritional status score lower,better nutrition status;symptoms of pain,insomnia,loss of appetite,nausea,vomiting,constipation coefficient is that it has significant and positive effect on nutritional status score,pain,insomnia,loss of appetite,nausea,vomiting,constipation score is high,nutritional status score is high,nutritional status worse.9 The current nutrition support,the survey of 101 cases of gastrointestinal cancer patients,good nutrition group,only one case patients receiving parenteral nutritional support;mild/moderate malnutrition group patients received parenteral nutrition support in 10 cases,no nutrition support in 41 cases;severe malnutrition group patients received parenteral nutrition support for 16 cases,no nutrition support in 16 cases,three groups of patients with nutritional support compared to the situation,severe malnutrition group accepted nutritional support percentage increased significantly(P =0.001).10 The patients with malignant PG-SGA score and NRS 2002 scoring bivariate correlation analysis.The results showed that the PG-SGA score with NRS 2002 score are significantly correlated Rs=0.337.Of all patients with malignant carcinoma were PG-SGA score and NRS 2002 score,results show,PG-SGA score of the detection rate of malnutrition was as high as 82.2%,and NRS 2002 method of malnutrition positive detection rate is only 29.7%,the difference was statistically significant(P <0.001).NRS 2002 score for the nutritional status of patients with good and application PG-SGA rating of 37 cases of mild / moderate malnutrition,severe malnutrition 16 cases.Conclusion:1 The nutritional status of patients with digestive tract malignant tumor is poor in most cases,malnutrition occurred at a higher rate,upper digestive tract malignant tumors of lower digestive tract malignant tumors are more likely to occur malnutrition.And malignant tumor patients with malnutrition and nutrition support rate is relatively low.2 Patients with malnutrition status affects the time of hospitalization,hospitalization expenses and the patient's overall quality of life and total protein level of patients with malnutrition,serum albumin level,BMI,triceps skinfold(TSF)non decreased and hand grip and left/right leg Zhou Jingjun more nutritious good.Pain,insomnia,loss of appetite,nausea,vomiting,constipation and other symptoms were can affect the nutritional status of patients,thereby affecting the quality of life.3 PG-SGA score and NRS 2002 score on the nutritional status of patients with malignant tumor evaluation results with correlation,but the PG-SGA score method of malnutrition and a higher rate of detection.We should pay attention to the evaluation of the nutritional status of the patients,for patients with nutritional support,so that patients benefit from it.