| Clerodendron trichotomum Thunb belongs to verbena green plant at hkust,with its’ leaves and twigs as Medicinal parts,and its’ another name is smelly wutong,backyard flower,jasmine and so on.It grows mainly in liaoning,gansu province and majority of east China,central China.on Abroad,it distributes in the northern Philippines,north Korea and other regions as well.Clerodendron trichotomum is more growing at an altitude of 2000 metres on hillslopes.Due to growth in haizhou area,it is called Haizhou dichroa.Smelly wutong was originally recorded in compendium of material medica shu,which contained paint figure by name,Su Song said ”Haizhou grows with,leaves like Chinese catalpa,red and white August flower,and blue color,like a mountain fruit and small.In the qing dynasty,Zhaoxuemin,Haizhou famous pharmacists,separated haizhou dichroa from the saxifrage dichroa,therefore haizhou dichroa is as a medicinal materials separately.With spicy and cool,Haizhou dichroa tastes sweetness and bitterness,it has the effects of killing the sects,clearing the damp,falling the blood pressure,etc,which is mainly used in clinical hypertension,rheumatism,malaria,bust the pain;According to reports in the literature,Haizhou dichroa has good effect of reducing the blood pressure effect,but the material basis for the blood pressure-lowering effect and function mechanism is not clear.This article will do in-depth research in the material basis.Haizhou dichroa belongs to the verbenaceae plants.In this paper,Chemical composition and pharmaceutical research of some representative medicinal plants are classified and summarized to evaluate the medicinalvalue of verbenaceae medicinal plants,which provide the important reference basis for futher scientific and rational use of Haizhou dichroa.Because the haizhou dichroa‘s maintenance management is easy,and is strong ability to resist pollutionSummer,with flowers autumn fruitand beautiful colour,it is as a good material arrangement of garden landscape,And at present,the research for the study of the chemical composition is more in pharmacognosy research and less rearch in Pharmacognosy.In order to further development and utilization of this drug,this experiment takes yantai,shandong province,nanjing,jiangsu province,jiangsu lianyungang haizhou and collected in different months eight dichroa samples.,its shape characteristics,microscopic characteristics,and etc,were studied.It provides the theory basis for the different months and the origin of haizhou dichroa leaf‘s biochemical identification and the development and utilization.On the basis of related research,the text takes haizhou dichroa extracted by75% ethanol diacolation herbs,and then with petroleum ether,ethyl acetate,n-butanol extraction in order to get the three parts extract.It uses macroporous adsorption resin,gel column chromatography,silica gel column chromatography to get a systematic research with its separation and purification of chemical constituents on the petroleum ether part and n-butanol part.It gets the ten monomer compounds through compound physical,chemical properties and UV,MS,1H-NMR,13C-NMR data analysis,etc.In combination with related literature,seven compounds were identified.There are β-sitosterol 、 lopeol 、 22-Dehydroclerosterol 、 pentadecanoic acid,D-glucopyranose,1,6-anhydro-β-D-glucose.Using of celery element reference substance,it establishes different regions haizhou dichroa HPLC fingerprint to laythe foundation for haizhou’s the specification of the drug. |
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