Point Embedded Wire Immersed In In Obese Rats Anti-rejection Drugs Gut Reaction Mechanism Research

Background As a common way to lose weight, meridian lines to buried law reducing weight to take the advantage of the needle is significant, its advantage in the gut into the body after, there will be a softening in the body, the decomposition of the body energy consumption such as liquefaction process, and it makes the dull autonomic nerve stimulation, an increase in energy consumption, make body fat decomposition of active neural function at the same time, thus can improve the curative effect of weight loss; And it makes the hypothalamic pituitary adrenal cortex and sympathetic adrenal cortical two system under the condition of stimulate acupuncture points to get adjustment, which are able to correct the disorder of endocrine, reduce the intake of energy. Gut, as a kind of foreign proteins, however, it can stimulate the body, and personal physical factors, light person can make patients bruises, fever, swelling, induration or serious appear even acupuncture rotting and collapse to form a fistula of the rejection, and these reactions are often appeared in the early stages of the acupuncture point bury line. Teacher after years of clinical use of dexamethasone injection,gentamicin injection,compound angelica injection infiltration gut of acupuncture point bury line to lose weight, a large number of clinical prove that this method can effectively reduce the acupuncture points in the process of the embedded wire rejection caused by gut, and low cost, simple and practical.Research method Select 55 healthy SD rats, male, 280 ~ 300 g weight(tongji university school of medicine, animal center, will be obese rats to build model in rats, to building a successful 50 obese rats were divided into four groups, the first and second groups(20, the third and fourth group 5 only. The first group of experimental group 1(medicine quad, buried line 1 month after death), experiment group 1 is divided into four subgroups, each component may only obesity rats, group A(dexamethasone injection) and group B(gentamycin injection) and group C(leaching of compound angelica injection), group D(immersion three drugs); A second group of experimental group 2(medicine quad, embedded wire 2 months after death), experiment is divided into four subgroups of two groups, each component may only obesity rats, group A(dexamethasone injection) and group B(gentamycin injection) and group C(leaching of compound angelica injection), group D(immersion three drugs); Third control group 1 group(not dip medicine quad, embedded wire 1 month after death). The fourth group control group 2(not dip medicine quad, embedded wire 2 months after death). 1 months after the first, three groups of obese rats anesthesia, first line take serum ELISA method to detect serum interleukin 2, gamma interferon levels. Then put to death, in obese rats embedded wire group, two months after the second, four groups of obese rats do the processing. Respectively taken by the organization for fixed, paraffin section and HE staining, the dye good slice under the microscope to observe, observe the take organization buried gut inflammation around the number of phagocytes in change. Using SPSS17.0 statistical software for experiment 1 group and contrast group, 2 group and control group of rats serum interleukin 2, level of the interferon gamma content changes, the number of phagocytes in the inflammatory response between groups of statistics. Experiment 1 group, 2 for the above two aspects of the way the experimental data.Consequence Experiment 1 group and contrast group, two groups and contrast between the two groups in the rat groups of experimental data contrast and found buried gut tissue around the phagocytes in the number of inflammation, interleukin 2 in serum of rats, gamma interferon levels are lower than not soak medicine gut rats; Experiment 1 group, 2 group rats in the experimental data contrast and found buried dip of the three drugs gut rat experimental data of the two aspects above are buried under separate three drugs gut data in rats.Conclusion Use three drug infiltration of the gut in acupuncture point bury a line therapy of rejection was significantly lower than immersion medicine gut, not separate application three drugs infiltration gut in acupuncture point bury line treatment of rejection, three drugs in combination with the method of infiltrating gut can more effectively help obese rats to reduce rejection reaction, and reduce the gut is buried around the organization to participate in the degree of inflammatory reaction of phagocytic cells, inhibit obesity rats immune response, thus, the research methods for the prevention and treatment of acupuncture point bury a line therapy in the gut of rejection is effective and can be implemented in clinical treatment.