The Adenocarcinoma Of The Uterine Cervix:A Analysis Of 52 Cases Of Ia-IIa Stage

Background and objective:Resrospective analysis the 52 cases of Ia-IIa stage of cervical adenocarcinoma that make a diagnosis and give a treatment in First Affiliated Hospital of Dalian Medical universty in Obstetrics and Gynecology from 2005.1 to2014.12,summarize the clinical and pathological features,Analyze the incidence trend of cervical adenocarcinoma,the role of MRI in preoperative diagnosis of cervical adenocarcinoma,how to determine the future of ovarian and the choice of surgical therapy,the prognostic factors of cervical adenocarcinoma.Methods: Resrospective analysis the 52 cases of Ia-IIa stage of cervical adenocarcinoma that make a diagnosis and give a treatment in First Affiliated Hospital of Dalian Medical universty in Obstetrics and Gynecology from 2005.1 to 2014.12,the clinical medical features include:the incidence trend,screening,MRI manifestation before operation,clinical stages,histologic type,parametrium invasion(PI),Lymph-vascular space invasion(LVSI),lymphatic metastasis,the risk factors and the transfer rate of ovarian metastasis,neoadjuvant chemotherapy(NACT),postoperative adjuvant therapy,state of recurrence and survival.and through the SPSS statistical software to analyze the corresponding data.Results: Through analysis the 52 cases of Ia-IIa stage of cervical adenocarcinoma,before five years cervical adenocarcinoma accounted for 9.68% of cervical cancer in hospital at the same period,After five years cervical adenocarcinoma accounted for 11.72% of cervical cancer in hospital at the same period.before five yearscervical adenocarcinoma incidence average age of 45.77±9.98 years,after five years cervical adenocarcinoma incidence average age of 48.12±8.67 years,compare two times the average onset age,statistics does not have the differences(P>0.05).52 cases of cervical adenocarcinoma in 12 cases wear tested by TCT,there are 9 cases appeared a certain degree of abnormal,the detectable rate was 75%.17 cases for HPV detection,the detectable rate was 82.35%.the detectable rate was 100% by combined use of them.these had a high coincidence rate by comparing the preoperative MRI results and postoperative pathologic results,the sensitivity of the preoperative MRI results in vagina involvement was 40%,the specificity was 85.18%.The sensitivity of the preoperative MRI results in ovarian metastasis was 50%,the specificity was 100%.the ovarian metastasis of cervical adenocarcinoma associated with FIGO staging,the ovarian metastasis of cervical adenocarcinoma of I stage was 0,but the ovarian metastasis of cervical adenocarcinoma of II stage was 33.33%,statistics does have the differences(P<0.05).In this study the risk factors of death 5 years including:FIGO stage,ovarian metastasis.It was irrelevant to age,pathological type,lymphatic metastasis,ovarian metastasis,vessel invasion,therapies and others on.Conclusion:1.The increase in the incidence of cervical adenocarcinoma,the cervical adenocarcinoma show younger trend..TCT combining with HPV is helpful to early detection and early treatment in screening cervical adenocarcinoma.2.These had a high coincidence rate by comparing the preoperative MRI results and postoperative pathologic results(because of fewer cases,fewer positive cases,other aspects ware not analyse.3.The ovarian metastasis of cervical adenocarcinoma associated with FIGO staging,.it was irrelevant to pathological type,lymphatic metastasis,utero-tissue infiltration,vessel invasion,age and others on.4.For Ia-IIa stage of cervical adenocarcinoma,FIGO stage and ovarian metastasis were risk factors that effected the prognosis.