Imaging Analysis Of The Relationship Between Carotid Atherosclerosis And Intracranial Atherosclerosis And Cerebral Infarction

Part one The relationship between carotid atherosclerosis and cerebral infarction Objective: To study the relationship between carotid artery IMT thickness, the plaque numbers and quantity,carotid artery stenosis and ischemic stroke Methods: Based on the control samples of 135 CI patients and 61 compared non-cerebrovascular disease patients in Fujian Medical college attached Xiehe Hospital from November 2014 to January 2015, to clarify difference of CAS plaque quantity, character and CCA-IMT between two groups through the color doppler ultrasound examination results of carotid artery. The numerical value of CCA IMT is less than 1mm be defined as normal, otherwise the IMT acuity is equal to 1mm be defined as thickening. The character of plaque is defined as:(1) the unstable plaque: including low echo plaques and uneven echo or hybrid echo plaques;(2) the stable plaque: including moderate homogeneous plaque and echo enhancement calcified plaque. The plaque numbers: unilateral detection shows more than one plaque is defined as multiple; unilateral detection shows one is defined as single. SPSS19.0 statistical software is used to analyse the collected data, enumeration data test using ?2, measurement data test using independent t samples. Results:(1) CCA-IMT Thickness: 76 patients(56.3%) in the CI patients are in normal data scope, thickening patients are 59(43.7%);46 patients(75.4%) in the control group are in normal data scope, thickening patients are 15(25.6%), P = 0.011 < 0.05. Suggesting that CCA-IMT is more common in CI patients.(2) Plaque stability: 92 patients in CI group are detected as unstable carotid atherosclerosis plaque, thus the incidence rate is 68.1%, in addition, there are 22 patients are belong to control groups, the incidence rate is 36.1%. P=0.025. Suggesting that unstable carotid atherosclerosis plaque is more common in CI patients.(3) Plaque numbers: in CI group,50 patients are defined as single CAS plaques, multiple patients are 44, sum to 96 patients totally; in control groups, the number of single and multiple patients are 16 and 10, sum to 26 patients, thus P=0.449>0.05. There is no direct correlation between the number of carotid atherosclerotic plaques and cerebral infarction.(4) The carotid stenosis patients in CI group are 12, of carotid stenosis is 12 people, including 5 mild stenosis patients, 4 moderate stenosis patients and 3 severe stenosis patients. Conclusion: The unstable carotid atherosclerosis plaque?CCA-IMT thickening and carotid artery stenosis are more common in CI patients. Part2 The relationship between carotid atherosclerosis and intracranial atherosclerosis and the types of CI. Objective: At first,we analyze the relationship between extracranial and intracranial arterial sclerosis,and then analyze the relationship between the nature and number of carotid artery plaque, the large intracranial artery occlusion and the type of cerebral infarction. Methods: The observation samples are 87 patients who performed cerebral MRA and carotid artery color ultrasonography examinations in our hospital from November 2015 to April 2015.Firstly, to analyze the pertinence between Intracranial and extracranial atherosclerosis based on the results of cerebral MRA and carotid artery color ultrasonography.Then the patients were divided into LACI group and CI group according to the clinical manifestation and the OCSP classification,to study the relationship between the nature and number of carotid artery plaque, the large intracranial artery occlusion and the type of cerebral infarction. Results:(1) Connection between intracranial and extracranial AS: extracranial AS patients are 78, cerebral MRA indicates the intracranial AS patients are 72, C=0.406,there was moderate correlation between intracranial and extracranial arteriosclerosis;(2) Connection between intracranial and extracranial AS and the types of CI: LACI stable plaques patients are 11, unstable plaques patients are 25, the CI patients with stable plaques are 2, unstable plaque patients are 29, P=0.029<0.05, suggesting that there is relationship between the quality of Carotid artery plaque and the type of cerebral infarction; in LACI group, the single plaque patients are 17, multiple plaques patients are 19, in CI group single plaque patients are 13, multiple plaques patients are 18, P=0.664>0.05,suggesting that there is no direct relationship between the number of Carotid artery plaque and the type of cerebral infarction;in LACI group, the patients with intracranial artery occlusion are 3, 10 patients in none LACI group get intracranial artery occlusion, P=0.034<0.03, suggesting that large arteries occlusion of LACI is more rare than non LACI. Conclusion:(1)There are related to intracranial and extracranial AS.(2)There was no significant correlation between the type of cerebral infarction and the number of carotid plaques, however, there was correlation between the type of cerebral infarction,the quality of the carotid artery plaque and the occlusion of intracranial large artery.The carotid artery with unstable plaque and the intracranial large artery conclusion in patients with cerebral infarction and carotid with unstable plaque multiple lacunar infarction.