The Situation Of The Acute Pain Indicators In Patients With Acute Pancreatitis And Their Influences On The Duration Of Hospital Stay

Aim:It’s a significant problem that patients with acute pancreatitis suffer acute pain drastically.However,the intractable situation was rarely reported.In this research,the present situation of the acute pain in patients with acute pancreatitis is to be surveyed and the its influences on the length of resident time is going to be analyzed as well.All the results of this research are in order to provide evidence-based references for the management of acute pain among the patients with acute pancreatitis.Methods:In this prospective study,there was 150 patients from two Top-three hospitals,ER-ICU and observation room of ER.The databases included patients’ basic information,clinical data and analgesia data.The incidence of moderate/severe pain,the accumulative total pain time(TPT)and the length of resident time in four hospitalized duration(0-2h,2-12 h,12-24 h,24-48h)were recorded and with NRS,the degree of pain was evaluated.In this research,the relative factors between acute pain and length of resident time are to be analyzed and the further detailed factors will be studied.Results:1.The patients during the four periods(0-2h、2-12h、12-24h、24-48h):1.1 The incidence of moderate/severe pain was 98.7%,94.7%,47.3% and 7.3%,which was fairly high in the 0-2h and 2-12 h durations.However,the incidence in the 12-24 h duration descended afterwards.1.2 The total time of moderate/severe pain was 1.97±0.24 h,5.22±3.00 h,2.05±2.70 h and0.27±1.04 h.1.3 The scores of NRS during the four periods were 8.06±1.55,5.25±1.23,3.34±1.17 and 1.59±1.15.As the time going on,the score of NRS is getting lower and lower.1.4 The total pain time was 47.20±26.00 h.2.The average length of resident time was 11.35±5.53 d.3.With Pearson Chi-Square test and Fisher Exact test,the relationship among the resident time and pleural effusion(r=0.28,P﹤0.01),seroperitoneum(r=0.32,P﹤0.01),Ranson Score(r=0.20,P﹤0.05),NRS score in the24-48h(r=0.29,P﹤0.01),complications(r=0.21,P﹤0.05),TPT(r=0.36,P﹤0.01),TPT of moderate/severe pain in the 2-12h(r=0.17,P﹤0.05),the incidence of moderate/severe pain in the 12-24h(r=0.17,P﹤0.05)and in the 24-48h(r=0.24,P﹤0.01)was analyzed.In a conclusion : the more severe the disease,the longer the TPT and TPT of moderate/severe pain in the 2-12 h,the higher NRS score in the 24-48 h duration may relate to the longer resident time.Patients with pleural effusion,seroperitoneum and complications could get a longer resident time.4.The multivariate logistic regression test was performed to screen that pleural effusion(B=2.52,P﹤0.05),Ranson Score(B=3.91,P﹤0.05),TPT(B=0.06,P﹤0.01)and TPT of moderate/severe pain in the 0-2h(B=-3.58,P﹤0.05)could be the independent risk factors of resident time.Conclusion:Acute pain in the patients with acute pancreatitis lasts long and the degree of the pain is severe.TPT and TPT moderate/severe pain in the 0-2h may have some effects on the resident time.Mild pain cannot be ignored during the pain clinical evaluation.Clinical medical staff should carry on positive and effective therapy to intervene the acute pain among the patients with acute pancreatitis as early as possible.