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Effect Of Liujundanshen Granule On BaPWV And ABI In Patients With Essential Hypertension Of Qi Deficiency And Phlegm And Blood Stasis Syndrome

Posted on:2018-08-08Degree:MasterType:Thesis
Country:ChinaCandidate:T DengFull Text:PDF
GTID:2334330512999545Subject:Internal medicine of traditional Chinese medicine
Abstract/Summary:PDF Full Text Request
Research purposes:The main purpose of this clinical study is to explore the treatment effect of Liujun Danshen Granule on primary hypertension of qi deficiency and phlegm syndrome,And to explore the effects of bagani,ABI,blood pressure,Hey,hs-CRP and other objective indicators.The treatment of qi deficiency phlegm-type primary hypertension in the mechanism for the six jun salvia granules in the treatment of qi deficiency phlegm-type primary hypertension to provide more effective clinical evidence.Research methods:The patients were divided into two groups:the control group and the treatment group,each group of 55 cases,a total of 110 cases The The random table is generated by spss17.0.The control group was given the basic treatment of western medicine:nifedipine controlled release tablets orally,and according to the blood pressure adjustment drug dose,in order to achieve blood pressure control in the normal level of the target.Treatment group in the basic treatment of Western medicine added to the six Jun salvia granules treatment.1 month for a course of treatment,observation of 5 courses.The levels of baPWV,ABI,symptom score,body weight,BMI,blood pressure,Hey and hs-CRP were significantly different from those before and after treatment.Result:1.There were no significant differences in the scores of primary and secondary syndromes between the treatment group and the control group before treatment(P>0.05).After treatment,the treatment group was superior to the control group,the difference between the two groups was statistically significant(P<0.05).The difference between the two groups was also statistically significant(P<0.05).2.Before and after treatment,the difference of baPWV and ABI between the treatment group and the control group was not statistically significant(P>0.05).After treatment,the difference between the two groups was statistically significant(P<0.05)In the control group,the same group of patients before and after treatment,the difference between the two groups was also statistically significant(P<0.05).After treatment,the treatment group of patients with atherosclerosis decreased by 20 cases,the control group only reduced in 3 cases,the difference between the two groups was statistically significant(P<0.05).3.Before and after treatment,the difference of Hey and hs-CRP between the treatment group and the control group was not statistically significant(P>0.05).After treatment,the treatment group was superior to the control group,the difference between the two groups was statistically significant(P<0.05).The difference of hs-CRP between the two groups was statistically significant(P<0.05).There was no significant difference between the two groups(P<0.05)>0.05).Compared with the same group,the difference of hs-CRP was statistically significant(P<0.05).4.The difference of systolic blood pressure,diastolic blood pressure and pulse pressure difference between the treatment group and the control group was not statistically significant(P>0.05).After treatment,the treatment group was superior to the control group,The difference was statistically significant(P<0.05).The difference of systolic blood pressure,diastolic blood pressure and pulse pressure difference between the two groups was also statistically significant(P<0.05).inConclusion:1.Six-Jun Danshen granules can better reduce the systolic blood pressure of the patients;2.Liu Jun Danshen particles can better reduce the patient's blood homocysteine level;3.Liu Jun Salvia particles can better reduce the patients The pulse wave conduction velocity,while improving the patient's ankle brachial index,reduce the incidence of atherosclerosis cases;4.Liu Jun Salvia particles can effectively reduce the patient's symptom score,improve the clinical symptoms of patients.
Keywords/Search Tags:essential hypertension, qi deficiency phlegm-stasis type, Liujundanshen granule, pulse wave velocity, Ankle brachial index
PDF Full Text Request
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