Clinical Analysis Of 72 Cases Of Borderline Ovarian Tumor

Objective: The objective of the present study was to analyze the clinical features,surgical methods and prognosis of patients with borderline ovarian tumor(BOT),guiding clinicians to choose the best treatment for different patients.Methods: A retrospective review of all patients treated for borderline ovarian tumor at the First Affiliated Hospital of Bengbu Medcial College from January 1,2012 to December 31,2015 was performed.We compared the clinical features,pathological types,laboratory and imaging examination,clinical stage,surgery and postoperative treatment,analyzed the prognosis.The information of all cases was came from the Medical Records and Statistics Room,Pathology Department and Ultrasonic Examination Room.Results: A total of 55 patients were identified.The median age was 44 years(range 18~85 years),and the average age was 45.21±16.19 years.The majority of the patients(84.7%)exhibited International Federation of Obstetrics and Gynecology(FIGO)stage I disease,and the remainder exhibited FIGO stage II / III(stage II 4.2%,stage III 11.1%).Serous histology was found in 60.0% of the cases,while mucinous was 37.5%,and the remainder was endometrial and the mixed.Among them,an elevation of the cancer antigen-125(CA125)serum level occurred in 54.2% of the cases.All patients underwent surgery,conservative surgery accounted for 44.4% of all patients(32/72),and radical treatment was 55.6%(40/72).There were 3 cases of patients with bilateral salpingo-oophorectomy and omentectomy,as a radical surgery.The recurrence rate of patients with fertility preserving surgery of stage I was significantly higher than that of radical surgery(P<0.05).Cystectomy was more likely to recur than the patients of unilateral adnexectomy.6.9% of all patients received adjuvant chemotherapy.Postoperative follow-up was 10~55 months.In total,only 1 case was dead because of the tumor,10.9% of all cases exhibited.Part of recurrent patients underwent surgical treatment,only 1 case exhibited canceration of part tumor.Conclusion: BOT has an excellent prognosis,and its clinical feature are not obvious.Surgery is the main treatment.Conservative surgery should be considered for patients of reproductive age who desire preservation of fertility.Patients with stage I can undergo unilateral salpingo-oophorectomy.A long-term follow-up is highly recommended for patients who underwent conservative surgery.Radical surgery can be recommend to those patients who don’t desire fertility.Postoperative adjuvant chemotherapy has little effect on BOT,and it is not recommended to undergo adjuvant chemotherapy.