Baijie Powder Dispersion Of Low Anal Fistula Postoperative Inflammatory Reaction And TNF-α、IL-6 Expression

PurposeWatch Baijie Powder scattered local external use in anal fistula low postoperative wound tissue of TNF-α and IL-6,explore the Baijie Powder’s early spread to alleviate postoperative anal fistula wound inflammation and edema and edge of related mechanisms,for the Baijie Powder’s clinical application to provide reliable basis,for the Baijie Powder’s ease analfistula postoperative wound of excessive inflammatory response to provide basic research.MethodsMeet the criteria for the selected hospital anus bowel division of 60 cases of hospitalized patients with anal fistula,low in anhui province were randomly divided into treatment group and control group,treatment group 30 cases and control group 30 cases.2 d all be anal fistula incision operation treatment,postoperative treatment,treatment group scattered rubbing with a clean bandage +Baijie Powder;The control group with clean bandage + article vaseline gauze for external use only.Postoperative2 d,5 d,8 d tong wound tissue 0.2g,using the double antibody ELISA method to measure wound tissue of tumor necrosis factor(TNF-α)and interleukin 6(IL-6),and compared two groups of treatment of postoperative wound edema.At the same time observe the adverse drug reactions,safety evaluation.ResultsTreatment on two groups of cases before sex,age,duration of wound area,the types of anal fistula,no statistically significant difference were observed in the balance comparison,comparable;Two groups in the process of treatment are safe and reliable,no adverse events;1.on the expression of TNF-α: 2 days after two groups of patients with serum concentration of TNF-α,contents of serum TNF-αtreatment there was no statisticallysignificant difference compared with the control group(P > 0.05);5,8 days after the content of serum TNF-α were lower in treatment group than the control group(P <0.01),there is an obvious statistical difference.2.In the expression of the IL-6:2 days after two groups of patients in the serum IL-6in comparison,the treatment group content of serum IL-6 there was no statistically significant difference compared with the control group(P > 0.05);5,8 days serum IL-6 levels were lower in treatment group than the control group(P < 0.01);Significantly statistical differences.3.on the wound edema,postoperative day 2 wound edema is similar between the two groups had no statistical significance(P>0.05);4,and 6 days after breast-conserving therapy groups lost edema wounds than the control group(P < 0.01),there is significantly statistical differences.Conclusion1.The anal fistula after postoperative wound using dragon’s white powder for external use,the treatment group of TNF alpha and IL-6 levels significantly lower than the control group,the treatment group is better than that of control group in terms of anti-inflammatory,Baijie Powder spread has also verified the anti-inflammatory adjustment.2.As the level of TNF alpha and IL-6,patients postoperative wound edema,said understand anti-inflammatory effect of dragon’s dispersion mechanism may be related to alleviate edema wounds.3.The Baijie Powder no obvious side effects in clinical application and clinical application of safety by preliminary affirmation,is worthy of popularization and application in clinical treatment.