Research Of Brain Evoked Potential In Ischemic Post Stroke Depression

Objective To explore the change of Brainstem Auditory Evoked Potential,Visual Evoked Potential and Event Related Potential P300 in ischemic-PSD patients.Methods Collected 121 cases of acute ischemic stroke patients from January 2015 to September 2015 in Affiliated Hospital of Youjiang Medical University for Nationalities. According to the DSM-V diagnostic criteria and HAMD-24 score, patients were divided into two groups: post stroke depression group (PSD) and non-post stroke depression group (non-PSD). Two groups accepted MMSE score, NIHSS score. 50 cases of healthy check-up as a control group. Collecting three groups of general clinical data and completing Brainstem Auditory Evoked Potential, Visual Evoked Potential and Event Related Potential examination.Results Gender, high cholesterol, high low-density lipoprotein and high homocysteine were associate with the occurrence of PSD (all P-< 0.05).Brainstem Auditory Evoked Potential’s V wave latency prolong was associate with the occurrence of PSD (P<0.05). Visual Evoked Potential didn’t associate with the occurrence of PSD (P>0.05). PSD’s HAMD score were positively correlated with NIHSS score and P300 latency period, but negatively correlated with MMSE score (P<0.05).MMSE score and P300 latency was negatively correlated (P< 0.05).Conclusion The incidence of PSD in female stroke patients higher than male stroke patients. High cholesterol, high low-density lipoprotein and high homocysteine might related to the occurrence of PSD; BAEP’s V wave latency prolong might relate to the occurrence of PSD; The heavier the degree of depression the more serious of cognitive impairment; MMSE score and P300 latency period could evaluate patients’ cognitive function.