| Objective: To compare the clinical efficacy and safety of proximal femoral locking plate and cannulated compression screw in the treatment of femoral neck fracture in young and middle-aged patients by Meta analysis.Methods: Through the computer search of the Cochrane library,Medline,Embase,Chinese journal full text database,Wanfang database and other resources,according to the inclusion and exclusion criteria from literature,extracting the relevant data,the data were analyzed by Rev Man5.3 statistical software Meta,comparison of femoral locking plate group and cannulated screws group Harris hip function score excellent rate,operation time,fracture healing rate,healing time of fracture,femoral head necrosis rate,intraoperative blood loss,postoperative long-term Harris hip function score,complication rate etc..Results: A total of 11 clinical trials and 728 patients were included in this study.Meta analysis showed that the operation time of proximal femoral locking plate [MD = 6.41,95%CI(-0.21,13.03),P =0.06],intraoperative blood loss [MD = 21.32,95%CI(-1.34,43.98),P =0.07],postoperative drainage [MD=(-18.22,-7.74,95%CI,P=0.15],time of fracture healing[MD =-1.56,95%CI(-5.24,2.13),P =0.41] with cannulated screws group had no significant difference.However,the excellent and good rate of postoperative hip joint function recovery was [OR=2.80,95%CI(1.68,4.65),P<0.0001],and the proximal femur hollow locking plate group was significantly higher than that of the hollow compression screw group.The total complications were [OR = 0.29,95%CI(0.11,0,37),P < 0.00001],proximal femoral hollow locking plate group was significantly lower than that of the hollow compression screw group.Conclusion:The long-term clinical results of femoral locking plate group with for the treatment of femoral neck fracture group is better than cannulated screws,but the surgery duration,intraoperative bleeding volume,and fracture healing time have no obvious difference.In the clinical work,the choice of therapy should be cautious.Due to the small amount of research and the quality is not high,the strength of the argument is weak,it is necessary to carry out and design a large sample randomized controlled study to further verification. |