The Value Of Otoacoustic Emissions Combined With ABR And ASSR In The Assessment Of Potential Risk In The Contralateral Ear Of Patients With Unilateral Sudden Deafness

Objective:To analyze the characteristics of contralateral otoacoustic emissions with,auditory brainstem response and auditory steady-state responses in patients with unilateral sudden deafness,and combining with the pure tone hearing threshold test to assess the status of the contralateral ear and the potential risk for unilateral sudden deafness in the medical process of the prevention and intervention of the contralateral ear to provide a clinical basis.Methods:1.A total of 80 patients with unilateral sudden deafness(18 to 60 years old)were enrolled in our department from January 2016 to December 2016,theIpsilateral 80 ears of the case of group A,the opposite side of 80 ears for the case B group,and selcting 40 nomoral humans for the control group.In the quiet or natural sleep state were pure tone hearing threshold test,otoacoustic emissions,auditory brainstem response and auditory steady-state responses.2.Rec-oding the response amplitude,response repeatability,signal-to-noise ratio of transiently evoked otoacoustic emission and each frequency detection rate,amplitude of distortion product otoacoustic emission,and ABR,AS SR,pure tone audition listening threshold and abnormal situation,including the prolongation of V-wave latency,interfacial latency(IPL),?-? interval difference(? IPL),etc.3.For statistical analysis,to compare the differences of otoacoustic emissions,ABR,ASSR and pure tone audiometry between groups;analyzing the correlation of ABR,ASSR and pure tone auditory thresholds in three groups.Results:1.The TEOAE response amplitude,response repeatability and signal-to-noise ratio of the cases A and B were significantly lower than that in control group,the difference was statistically significant(P<0.05).2.The detection rate of DPOAE in group A and B was lower than that in control group at both 0.75,1.0,2.0,4.0,6.0 and 8.0 kHz except 1.5KHz,the difference was statistically significant(P<0.05);DPOAE amplitude of the case group in the 0.75-8.0KHz frequency were lower than the control group,the difference was statistically significant(P<0.05).3.The ABR ?-wave and V-wave latency,?-? wave interval results of cases A,B group were more extend than,that in control group,cases A,B group ? IPL were higher than the control group,the above differences were statistically significant(P<0.05).The response threshold of ABR and ASSR in group A was significantly higher than that in control group(P<0.05),but there was no significant difference between group B and group B.4.Compared with the control group,the' frequency threshold of pure tone audiometry was significantly higher than that in the control group(P<0.05).There was no significant difference between the two groups.Compared with ABR and ASSR,the results of the three methods showed that the results of the three methods were highly correlated with each other.The positive rate of ASSR was higher than that of ABR in case A group,the difference was statistically significant(P<0.05).5.Among the test results,the positive rate of ASSR in group A was higher than that in ABR and higher than that of pure tone audiometry,the difference was statistically significan(P<0.05)t.In group B,the positive response rate was from high to low:DPOAE>TPOAE,ASSR>ABR>pure tone audiometry,the difference was statistically significant(P<0.05).Conclusions:Some patients with sudden deafness of the contralateral ear has been early cochlear dysfunction,The use of otoacoustic emission combined with ABR and ASSR in the detection of sudden deafness can be more comprehensive and more accurate analysis of the impact of monkeys on the potential of the contralateral ear,and further for clinical work and daily life to prevent the loss of hearing loss provide the basis.