Analysis The Risk Factors Of Anterior Communicating Aneurysm Rupture

Objective:Intracranial aneurysm rupture accounts for 80%of subarachnoid hemorrhage.Anterior communicating artery is the most occurrent site.Because the morphology of anterior communicating artery is complext,the risk factor of aneurysm rupture has its specificity.Currently,there is rare analysis on anterior communicating artery.The objective of this article is to analyze the infleunce of clinical factors and arterial aneurysm morphological feature on aneurysm rupture.Methods:138 cases with anterior communicating aneurysms that had been admitted in our hospital from January 2013 to November 2016 were included in this study and they all underwent whole cerebral Digital Subtraction Angiography(DSA)or Magnetic Resonance Angiography(MRA)imaging or CT angiography(CTA).Anatomical data and clinical materials of anterior communicating aneurysms were collected and single factor or multiple factor logistic regression analysis was adopted.Results:Blood glucose(P=0.038),systolic pressure(P=0.036),diastolic pressure(P=0.046),length of arterial aneurysm(P=0.013),width of arterial aneurysm(P=0.037),neck diameter of aneurysm(P=0.014),A1-A2 angle≤100,daughter ascus(P=0.0006)of patients suffering from anterior communicating aneurysms before and after rupture had statistical difference.In multiple factor logistic regression analysis,blood glucose(P=0.003;OR,4.19;95%CI,1.615-10.899),neck diameter of aneurysm(P=0.0089;OR,2.14;95%CI,1.201-3.819),daughter ascus(P=0.0033;OR,12.94;95%CI,2.339-71.604)are independent risk factors of anterior communicating aneurysm rupture.ROC curve of aneurysm neck width indicated the best predicating for aneurysm rupture value was 3.79mm(area under the curve 0.66;95%CI,0.534-0.786).A1-A2 angle ROC curve indicated the best predicating for aneurysm rupture value was less than 98 degree(area under the curve 0.619;95%Cl,482-0.755).Conclusions:The neck diameter of aneurysm over 3.79mm,daughter ascus and A1-A2 angle less than 98 degree can be indepdent risk factor of anterior communicating aneurysm rupture.