| Objective:The aim of the study was to evaluate the effect of the screening of BI-RADS(Breast imaging reporting and data system)classification combined ultrasound elasticity imaging and to provide a scientific basis for women’s early screening and diagnosis of breast cancer.Methods:131 patients with mammary gland nodules who were tested using breast ultrasound in the hospital from January 2015 to October 2016.The typical cystic masses and the cystic--based mixed tumors were not included.All solid nodules were removed by surgeons and were done histopathological examination.The age range is from 15 years old to 83 years old.The average age is 45.3±10.5 years.The instrument was HITACHI Erlangshen ultrasonic diagnostic apparatus and the probe frequency was from 6MHz to 13 HMz.Patients were firstly examined by using conventional ultrasound.Secondly,they were examined by using ultrasound elastography technology.All solid nodules were conducted UE score and measured their strain ratio.The SPSS 19.0 were used to analyze the date.The accuracy,sensitivity,specificity,positive predictive value,negative predictive value of four methods were calculated.The chi--square test was used to observed if the difference of various methods was statistically significant.Results:(1)The sensitivity of conventional ultrasound in diagnosing breast solid nodules was 78.13%,the specificity was 83.26%,the accuracy was 82.61%,the positive predictive value was 40.32% and the negative predictive value was 96.34%.(2)The elasticity mark ≥4 was defined malignancy.The accuracy,sensitivity,specificity,positive predictive value,negative predictive value of evaluation of benign and malignant solid nodules by using the ultrasonic elastography scoreing method were 83.97% 、75.00% 、87.37% 、69.23% 、90.22%。(3)The best diagnostic critical threshold of the strain ratio of the solid nodules of benign and malignant was 3.12.SR≥3.12 was defined malignancy.The accuracy,sensitivity,specificity,positive predictive value,negative predictive value of evaluation of benign and malignant solid nodules by measuring the strain ratio were 84.73% 、80.56% 、86.31% 、69.05% 、92.13%。(4)The accuracy,sensitivity,specificity,positive predictive value,negative predictive value of evaluation of benign and malignant solid nodules by using conventional ultrasound combined with ultrasonic elastography score were 87.02% 、 97.22% 、83.16% 、 68.62% 、98.75%。(5)The difference of accuracy、 sensitivity、 specificity of pairwise of four methods was compared.The sensitivity of conventional ultrasound combined with elastography score was higher than the other of each method and their difference was statistically significant(P<0.05).The specificity of conventional ultrasound was higher than conventional ultrasound combined with elastography score and their difference was statistically significant(P<0.05).Conclusion:1.Using conventional ultrasound,ultrasound elastography score,the Strain Ratio of elastography,conventional ultrasound combined with elastography score to identify benign and malignant solid nodules of the breast all have a certain diagnostic value.But it was no statistically significant between the application of ultrasound elastography technology and application of conventional ultrasound in the differential diagnosis of breast solid nodules of benign and malignant.2.Conventional ultrasound combined with ultrasound elastography score can improve the diagnostic sensitivity of malignant nodules and early breast cancer detection rates and can possibly realize the early detection,early diagnosis,early treatment.Ultrasound elastography is a useful complement to conventional ultrasound diagnostic. |