Establishment Of Refractive Files For Children Aged 8 To 12 And Preliminary Analysis Of Myopia Prevention And Control Program

Obsjective: To establish the 8-12 years-old children refractive files and supplement our hospital refractive epidemiological data.And to initially evaluate the effects of myopia control with single vision spectacle lenses and orthokeratology lenses for 6 months.Methods: 1.We established the refractive files of 8 to12 years old children from Fujian Medical University First Affiliated Hospital refractive clinic in December 2015 to March 2017.The items were recorded in these files,including eye position,the eye movement,uncorrected visual acuity,non-contact intraocular pressure,dominant eye,cycloplegia refraction,fundus,mydriatic refraction,best-corrected visual acuity,and measured axial length,central cornea thickness,aqueous depth,lens thickness,corneal curvature and other refractive elements by LENSTAR,which updated every six months.And We analyzed the refractive files of 8-12 children were used to exclude special eye diseases,by paired t test,independent t test,variance analysis,person correlation test and other statistical methods.2.Retrospective analysis of our hospital 8-12 children refractive files,excluded the disease and family history,Whose sphere arranged from-0.50 D to-6.00 D,astigmatism ≤-1.50 D.In the first 6 months,children wore single vision spectacle lenses,and in the second 6 months,children wore orthokeratology lenses.Then we compared the changes of diopter and axial length in the first and second 6 months by paired design.Results: 1.We established 323 eligible children refractive files.The childrem’s average age was 10.24 ± 1.41 years old,including 154 males and 169 females.81.4% children were right type.91.33% were myopia.68.11% children with different degrees of astigmatism,in which 91.91% were astigmatism with the rule.2.The axial length and aqueous depth of the males were significantly shallower than that of the females(t=7.089,P<0.01).that is,the corneal anterior surface(P <0.01).As to corneal anterior surface,boys’ were more flat than gils’ s(tk1=-8.646,P k1<0.01;tk2=-8.847,P k2<0.01).3.The difference of refractive elements and spherical equivalent refraction between right and left eye was not statistically significant.4.With the increase of age,the mean spherical equivalent refraction developed in the direction of myopia and the axial length growth was the same,and the difference was statistically significant(FSER=16.39,PSER<0.01FAL=17.88,PAL<0.01).And the difference of aqueous depth and lens thickness are statistically significant,too(FAD=9.87,PAD<0.01;FLT=17.88,PLT<0.01).5.Compared with different diopter groups,the axial lengths had significant difference(F=12.783,P<0.01).6.The axial length(r = 0.726),the lens thickness(r = 0.117),the flat meridian(r =-0.099),the steep meridian(r=-0.100),the mean corneal curvature(r =-0.103),and the axial / corneal curvature(r =-0.822)were significantly correlated with the spherical(P <0.05).7 When the axial / corneal curvature = 3.07,the sensitivity of the refractive state to myopia was 87.9%,the specificity was 86.1%,the Jordan coefficient was 0.74;8.Compared with wearing single vision spectacle lenses for 6 months,the changes of diopter and axial length were significantly less during the 6 months wearing orthokeratology lenses.Conclusion: 1.The establishment of children’s refractive files can help to improve the children’s refractive epidemiological data,predict the occurrence of myopia,and make personalized response in time;2.Orthokeratology lenses are better than single-lens glasses in control the myopia development.