| purpose:Explore the coronary heart disease(CHD)heart failure in acute aggravating period involves the syndromes elements,medication rule,and summarized,for later on the dialectical analysis of the disease to provide a certain basis;Professor analysis Deng Yue treatment of coronary heart disease(CHD)heart failure in acute aggravating period of experience,the formulas that early curative effect evaluation,provide experience for the treatment of the disease.Methods:1.Case retrospective survey study: 204 cases of coronary heart disease,heart failure in patients with acute aggravating period of clinical data,diagnosis and incorporated into the standard,using "syndrome retrospective questionnaire" syndrome.Collect patients using the prescription at the same time,the use of statistical methods to obtain evidence law of syndrome elements and drug related data,using SPSS19.0 establish a database for statistical analysis.2.Experiment study: into the group of 60 patients were randomly assigned to the control group and treatment group.Western medicine treatment specification of control group,treatment group norms western medicine treatment + Deng Yue professor experience.Treatment for 3 weeks.Into the group of patients before and after the treatment respectively to detect the NT-proBNP,LVEF,heart function grading,TCM syndrome score,quality of life score,determine the efficacy of treatment.Results: Retrospective study results1.Coronary heart disease and heart failure in acute aggravating period of disease elements of statistical results show that the single elements according to the frequency as follows: blood stasis,qi deficiency,Yin deficiency,water to drink,phlegm turbidity,Yang deficiency,and qi stagnation,blood deficiency.Virtual syndrome elements in the order: qi deficiency,Yin deficiency and Yang deficiency,blood deficiency;Solid syndrome elements in the order: blood stasis,drinking water,phlegm turbidity,and qi stagnation.2.Real venereal sex element combination according to the frequency as follows: blood stasis,phlegm turbidity and blood stasis and water to drink,pure blood stasis,drink water + phlegm turbidity and blood stasis + water + phlegm turbidity,other combinations are relatively rare.Virtual syndrome factor combination according to the frequency as follows: deficiency of + Yin deficiency,qi deficiency pure,pure Yang deficiency,Yang deficiency,Yin deficiency and qi deficiency and blood deficiency is a rare situation.3.Coronary heart disease,heart failure in patients with acute aggravating period was generally more complex,the single factor of syndrome and double factors is relatively rare,syndrome elements combination mainly include two categories: the three factors,the four factors.Among all syndromes elements combination,with qi deficiency,Yin deficiency and phlegm turbidity + the most proportion of blood stasis,followed by qi deficiency,blood stasis and water to drink,qi deficiency,Yin deficiency and blood stasis,Yang deficiency,blood stasis and water drink + phlegm turbidity;Of Yang deficiency,Yin deficiency and blood stasis,drinking water,deficiency and blood deficiency drink + water + phlegm turbidity,deficiency of qi and blood stasis in patients drink + water + + syndromes of elements is a rare combination.4.A factor in disease,in addition to heart,phase and the elements according to the frequency of a size for the disease,lung,kidney,spleen,liver,stomach and other using drugs regularity:1.Drugs according to frequency of usage categories from more to less in the order: phlegm,the water and blood,nourishing Yin,replenishing qi,explored,spleen,nerves,disappear.2.Yiqi class six appeared before the frequency respectively is: astragalus,codonopsis,atractylodes,rhodiola,bask in ginseng,liquorice;Yin class six appeared before the frequency respectively is: radix ophiopogonis,radix rehmanniae,lily,jade bamboo,caulis dendrobii,rhizoma anemarrhenae.The six water before class appear frequency,respectively is: poria cocos,alisma,semen plantaginis,grifola,coix seed,wormwood;Phlegm class six appeared before the frequency respectively is: white mulberry,pinellia,semen lepidii,bamboo shavings,snakegourd fruit,almond;Blood type appear frequency before 6: salvia miltiorrhiza,rhizoma ligustici wallichii,angelica,red paeony root,peach kernel,safflower,Appear this kind of frequency before six are: dried ginger,cassia twig,cinnamon,monkshood,epimedium,cummin;Qi class appear frequency before 6: semen raphani,amomum villosum,magnolia officinalis,radix bupleuri,bitter orange,flowers;Six nerves before class appear frequency,respectively is: zizyphus jujube kernel,keel,raw oysters,polygala,cortex albiziae,tuber fleeceflower stem.The experiment results:1.In the NT-proBNP,LVEF,two groups of treatment all can improve heart failure in patients with acute aggravating period of biological indicators,but the treatment group is better than the control group(P<0.05).2.In terms of cardiac function classification effect assessment,the treatment group is significant in improving cardiac function(P<0.05).3.In the live scores for treatment,two groups of treatment all can improve the patients quality of life,the treatment group effect obviously better than the control group(P<0.05).4.In the aspect of TCM syndrome score,two groups of treatment all can improve the symptom of the patients,the treatment group effect obviously better than the control group(P<0.05).5.Efficacy of syndromes,the treatment group is better than the control group(P<0.05).Conclusion:1.Coronary heart disease,heart failure in patients with acute aggravating period syndrome complex,but from qi deficiency,Yin deficiency and Yang deficiency,blood stasis and phlegm turbidity,water to drink,the six categories.2.Syndrome elements of blood stasis,phlegm turbidity,water to drink,three general in heart failure with acute aggravating period appeared at the same time,a mutual disease,qi deficiency and Yin deficiency syndrome in virtual sex element of occurrence probability is bigger,reflect "gas","Yin","stasis","water","phlegm" pathogenic theory.3.Of drug law also with replenishing qi,nourishing Yin and blood,water,eliminating phlegm to give priority to.4.Western medicine standardization of experience representing party and therapy for the treatment of coronary heart disease heart failure in acute aggravating period effect is obviously better than pure western medicine standardized treatment.Parties representing the experience of coronary heart disease(CHD)heart failure acute aggravating period of qi and Yin deficiency,phlegm and blood stasis patients with each other by water treatment effect significantly,can significantly improve the patient’s symptoms,improve patients with LVEF,improve heart function,decrease the NT-proBNP,improve survival in patients with treatment. |
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