Stuty On The Correlation Between ACT,PEF And FeNO Test With Medication Compliance Of Patients With Asthma

Objective: To study the correlation between asthma control test(ACT),peak expiratory flow rate(PEF),fractional exhaled nitric oxide(FeNO)with medication compliance in bronchial asthma patients,and to explore the clinical significance of the three methods in evaluating the compliance of patients with bronchial asthma.Methods: The subjects were selected from patients with bronchial asthma who had been treated in the outpatient department of our hospital from May 2016 to August according to inclusion criteria and exclusion criteria.Prior to the start of the study,participants were trained in knowledge about asthma and related skills in this study,and these skills were assessed.The ACT score,PEF,and FeNO values were measured and recorded at monthly follow-up visits,and the household drug use was monitored at the same time.The study lasted for 3 months,and all the data were collected and collated.43 subjects(male 22 cases,female 21 cases,age: 20-72 years old)were randomly grouped according to the following criteria: According to the ACT score ≥20 points or <20 points,they were randomly divided into two groups;According to the PEF pred% ≥80% or <80%,they were randomly divided into two groups;According to the FeNO value ≥25bbp or <25bbp,they were randomly divided into two groups;In accordance with the compliance assessment value% ≥80% or <80%,they were randomly divided into two groups again.The value of medication compliance between the matched groups was compared and statistically analyzed.Observing the difference of ACT score,PEF pred% and FeNO value in the different medication compliance value groups,and the data were statistically processed.The correlation analysis was carried out with ACT value,PEF pred% and FeNO value as independent variable,and compliance evaluation value as dependent variable.Results: 1.The medication compliance for 3 months of patients with ACT score ≥20 was evidently better than that with score <20,and the difference between the two groups was statistically significant(P<0.05).2.The medication compliance for 3-months of patients with PEF pred%≥80% was evidently better than the patients with PEF pred%<80%,and the difference between the two groups was statistically significant(P<0.05).3.The medication compliance for 3-months of patients with FeNO value <25ppb was evidently better than the patients with FeNO value ≥25ppb,and the difference between the two groups was statistically significant(P<0.05).4.The ACT score and PEF pred% in the good medication compliance group(≥80%)was significantly higher than the poor medication compliance group(<80%),and the changes was on the contrary in FeNO value.The differences between groups all had statistical significance(P<0.05).5.The ACT score and PEF pred% were positively correlated with medication compliance(%),but the FeNO value was negatively correlation.The difference between the matched groups was statistically significant(P<0.05).Conclusion: In asthma patients,ACT scores,PEF pred% and FeNO values have a good correlation with medication compliance.