The Correlation Among Exhaled Nitic Oxide, FEVI% Pred Of Lung Function Test And Asthma Control Test (ACT) Scales In Patients With Non-acute Episode Asthma

Background:Chronic airway inflammation is the essence of asthma.As the changeability and variability of asthma symptoms,asthma patients need long-term standardized treatment.We can see that evaluating airway inflammation and the level of clinical symptoms of asthma control have a very important clinical significance.Objective:To investigate whether fractional ehaled nitric oxide(FENO)or FEV1%pred of lung function test is able to reflect the degree of asthma control status.To explore the correlation among FENO,FEV1%pred and ACT scales is the aim to provide a reference to non-acute episode asthma treatment and management.Methods:The 107 cases of non-acute episode asthma that we selected are from Clinic of Respiratory Medicine in the First Affiliated Hospital of Nanchang University in2017.01-2017.05.Diagnostic standard is those described in “ Global Initiative for Asthma”(GINA 2016).A total of 142 candidates participated in the test.We divided them into 4groups:37 cases of asthma control group,35 cases of partial control group,35 cases of uncontrol group,normal group of 35 cases.We performed fractional exhaled nitric oxide test and pulmonary function tests.All the selected candidates were asked to complete the asthma control test(ACT)scales.The results were analyzed by SPSS19.0.Results:1.1)The result were significantly different in FENO between Asthma group and the normal group,statistically significant,P<0.05.2)We divided the control group,partial control group into a subset,and compared FENO between the subset and the uncontrol group.There is a significant difference between them.3)The result were no significant difference between the control group andpartial control group in FENO.2.We can see no significant difference in FEV1%pred among the 4 groups,no statistical significance,P>0.05.3.The score of asthma control test(ACT)scales in 4 groups showed a positive correlation with FEV1%pred while it had no significant correlation with FENO.FENO in the 3 asthma groups have no significant correlation with FEV1%pred.Conclusion:1.The values of FENO can not reflect the level of asthma control.It can be used in the differential diagnosis of asthma.2.FEV1%pred can not assess the level of asthma control status as an independent indicator.Assessing the level of asthma control status requires comprehensive ways.3.FENO of the 3 asthma groups have no significant correlation with FEV1%pred.FENO,FEV1% and ACT scores shoule all be used to assess asthma control starts.