Study On Association Of Working Hours And Occupational Physical Activity With The Occurrence Of Coronary Heart Disease In A Chinese Population

Objective: Many studies have shown that working for long hours are harmful to health,especially in the cardio-cerebrovascular disease.However,few studies have been made on the relationship between working hours and the amount of occupational physical activity(OPA)with coronary heart disease(CHD).The aim of this study is to explore the association of working hours and OPA with the occurrence of CHD in a Chinese population.Methods: During the period from December 2015 to October 2016,we conducted observational study in the First Affiliated Hospital of Nanjing Medical University,and a total of 595 participants were enrolled in the study.According to the results of their first coronary angiography(CAG),the subjects were divided into CHD group(N=354)and non-CHD group(N=241).All the lifestyle characteristics and work-related data of the participants were obtained through face-to-face questionnaires,and logistic regression analysis was conducted to examine the association of working hours and OPA with the occurrence of CHD.Results: Compared with non-employed people,long working hours(especially ≥55 hours/week)contributed to the occurrence of CHD(adjusted odds ratio[OR]= 2.212,95% confidence interval [CI]: 1.124-4.352,P=0.022)after multivariate adjustment in the Chinese population.With the extension of worktime,the CHD risk increased(P for the dose-response trend=0.023).Meanwhile,we found that the risk of CHD increased with the amount of activity decreased at work,and the linear relationship between the two was statistically significant(P =0.004).This relationship still existed even after adjusting for engagement in physical activity during leisure time and other characteristic factors(P= 0.010).Among them,there was the highest risk of CHD in the sedentary occupation(adjusted OR = 2.795,95%CI:1.527-5.118,P = 0.001).Conclusions: Long working hours and sedentary behavior at work are associated with a high risk of CHD in a Chinese population.In addition,prolonged working hours in sedentary occupations increases the risk of CHD,independent of engagement in leisure time physical activity.