| Objective We intend to compare the clinical benefit of acute hypertensive intracerebral hemorrhage patients after different intensity blood pressure administration,analyze the impact of Intensive antihypertensive treatment on the clinical benefit of patients with different hemorrhage sites and whether they can reduce SBPV.In order to explore more reasonable ways of managing blood pressure.Methods Participants with hypertensive intracerebral hemorrhage who was treated in General Hospital of Ningxia Medical University,During January2015 to December 2016 are our samples.We collected complete clinical data from patients.Based on the following conditions:1.hypertensive intracerebral hemorrhage;2.admission to hospital within 24 h after symptom onset;3.initial SBP> 140 mm Hg,giving antihypertensive treatment immediately;4.mean SBP≥120mm Hg and <140mm Hg within 1w 5.reached SBP<140mm Hg and maintain after admission 4-6h;screening for intensive group cases.Based on the following conditions: 1.hypertensive intracerebral hemorrhage;2.admission to hospital within 24 h after symptom onset;3.initial SBP> 140 mm Hg,giving antihypertensive treatment within 1w in hospital;4.mean SBP ≥140mm Hg and<180mm Hg within 1w;5.admission 4-6h has been achieved SBP <180 mm Hg and ≥140 mm Hg and maintained;screening for control group cases.reached SBP<180 mm Hg and ≥140 mm Hg and maintain after admission 4-6h;screening forcontrol group cases.Then compare the early clinical benefit between the two groups,the impact on SBPV,and compare the early clinical benefit between the two groups of patients with different bleeding sites such as basal ganglia,thalamus,lobe,and subcolumn.Following-up patients at the 12 th month after discharge showed m RS scores.Long-term clinical benefit was compared between the two groups.Results The duration of hospitalization in the antihypertensive group was12.0 days(9.0,17.03),serum creatinine was 85.30 μmol/L(61.15,100.20),urea was 7.73 mmol/L(5.38,10.34),and pulmonary infection was 17(34%);The hospitalized days were 15.0 days(12.8,21.0),serum creatinine was 74.25μmol/L(65.18,94.28),and urea was 5.88 mmol/L(4.31,9.23)in 32 lung infections(61.5%).Twenty-nine patients with basal ganglionic hemorrhage in the antihypertensive group were strengthened.The difference between the NHISS score was 2.0 points(1.0,4.0),and the thalamic hemorrhage was 9 cases.The difference in NHISS score was 3.0 points(2.0,4.0);in the normal blood pressure group,there were 28 cases of basal ganglia hemorrhage.The difference between NHISS scores was 1.5 points(0.0,3.0),and thalamic hemorrhage was found in 8 patients.The NHISS score difference was 1.5 points(0.5,3.5).Twenty-nine patients with basal ganglionic hemorrhage in the antihypertensive group were strengthened.The difference between the NHISS score was 2.0 points(1.0,4.0),and the thalamic hemorrhage was 9 cases.The difference in NHISS score was 3.0 points(2.0,4.0);in the normal blood pressure group,there were 28 cases of basal ganglia hemorrhage.The difference between NHISS scores was 1.5 points(0.0,3.0),and thalamic hemorrhage was found in 8 patients.The NHISS score difference was 1.5 points(0.5,3.5).The above differences were statistically significant(P<0.05).Blood loss,hematomaenlargement,NIHSS score,NIHSS score reduction,GCS score,transaminase,number of deaths,urinary tract infection,venous thromboembolism,and liver/kidney damage in the two groups after treatment.Months after the m RS score,good prognosis,poor prognosis,and the clinical benefit of patients with brain lobe and subcolumn hemorrhage,the difference was not statistically significant(P> 0.05).Conclusions 1.Antihypertensive treatment conducive to neurological deficit recovery for basal ganglia,thalamic hemorrhage.2.Antihypertensive treatment can reduce the day of hospitalization and risk of pulmonary infection;it may increase serum creatinine and urea,but it is still within the normal range.3.Antihypertensive treatment can reduce acute phase SBPV.4.Antihypertensive treatment failed to improve the quality of life of patients and reduce long-term mortality. |