The Clinical Efficacy Of The Treatment Of Rheumatoid Arthritis In The Treatment Of Rheumatoid Arthritis

Objective:Mainly assess whether the method of Touxietongbi is safe and effective in treating rheumatoid arthritis.Methods:A prospective clinical controlled observational study was conducted.40 RA patients meeting the inclusion criteria were divided into treatment and control groups.The control group received methotrexate 15 mg qw and folic acid 10 mg qw.The treatment of RA with Long Teng addition and subtraction,the prescription medicine by the Chuanshanlong 50g,Qingfengteng 30g,Rendongteng 30g,Luoshiteng 20g,Qinghao20g,Baishao 20g,Angelica 20g.Qi deficiency;plus 30-60g Huangqi;partial blood deficiency plus Shudihuang 20g;blood stasis,plus Danggui,Honghua 15g;damp heat,plus Yiyiren 30g,Fuling,Zhimu,Huangbo each 15g;The cold and humid,plus Mahuang,Guizhi each 10g,Han Sheng cold pain plus cinnamon,system Rougui,Zhifuzi 10g,kidney deficiency,plus Duhuo,Sangjisheng30g.Method of taking:Shuijian,daily pay,after breakfast and dinner,2 times a day,while oral methotrexate 15mg qw,folic acid 10mg qw.The observation period is 24 weeks.The clinical symptoms,laboratory indicators,and immunological indicators of the two groups were evaluated before and after the self-treatment within the group and the efficacy comparison between the two groups was used as a basic research program.Research results:In this study,we observed the clinical efficacy of the transfusion method in patients with RA and found that within the group comparison:through the paired sample t test,the number of tender joints,number of swollen joints,rheumatoid factor,The anti-CCP antibody,C-reactive protein,hemoglobin,and HAQ scores were all P<0.05,which were significantly improved compared with those before treatment.However,the control group had no significant improvement compared with that before treatment at 12 weeks and 24 weeks after P>0.05.The erythrocyte sedimentation rate and DAS28 treatment group started to take effect at 12 weeks,while the control group only took effect at 24 weeks.The morning stiffness time treatment group was effective after 24 weeks,and the control group achieved significant improvement at 12 weeks.The symptoms of TCM,VAS scores,GH scores,and joint function grading were significantly improved in both groups before treatment.Comparison between groups:Through independent sample t-test,the number of swollen joints,TCM symptom scores,ESR,DAS28 scores,and VAS score improvement after 12 weeks of treatment were compared with the control group,P<0.05,with statistics The significance of learning is that the treatment group is superior to the control group and has the advantage of quick effect.After 24 weeks of treatment,the number of patients with tender joints,morning stiffness,RF,anti-CCP antibodies,CRP,HGB,and HAQ scores improved better than the control group.There was no significant difference between the two groups in GH scores and joint functional grading.In terms of immune parameters,after 24 weeks of treatment,using the method of clearing the evil,the expression of CD3+ CD8+ could be up-regulated,CD3+ CD4+ and CD4/CD8 could be down-regulated,P<0.05,which was statistically significant.There were significant differences between the two groups.Compared with the overall efficacy of the group,the total effective rate of the treatment group was 85%,and the total effective rate of the control group was 65%.The overall curative effect of the treatment group was better than that of the control group.In terms of safety evaluation,serious adverse reactions such as severe infection and renal failure did not occur in the treatment group and the control group,and adverse reactions were manifested in abnormal liver function and menstrual disorders.In the control group,there were 1 case of elevated transaminases and 2 cases of menstrual disorders.There was no increase in transaminase and menstrual disorders in the treatment group.A transient increase in transaminases improved within 12 weeks of treatment with a protective liver medication after 2 weeks.Conclusions:The study found that both groups were effective in treating rheumatoid arthritis,and that the group known for clearing the evil and eliminating phlegm was more effective and had fewer side effects.This study will help establish a standardized treatment model,an effective drug evaluation system,and a more optimized diagnosis and treatment plan.Traditional Chinese medicine decoction can regulate the immune system balance,reduce synovial inflammatory changes,inhibit joint bone destruction,and reduce the occurrence of disabling events.Enhance the patient’s self-care ability,with scientific research and clinical value.