Clinical Study On The Treatment Of GGO Phenotype Early Non-small Cell Lung Cancer By Video-assisted Thoracoscopic Anatomic Segmentectomy And Lobectomy

Objective:The aim of this study was to investigate the curative effect of minimally invasive pulmonary anatomic segmentectomy and minimally invasive lobectomy for the treatment of non-small Cell Lung Cancer(NSCLC)with ground glass opacity(GGO)as the main phenotype.Methods:Retrospective analysis was performed on 72 cases of GGO NSCLC patients admitted to our hospital from January 2015 to January 2017.All patients were given complete preoperative examination and surgical treatment under the conditions of indications.According to the operation method was divided into lung group(27 cases)and pulmonary segment group(45 cases).Observed and recorded two groups of patients with intraoperative bleeding,operation time,chest drainage volume,thoracic drainage tube retention days,lymph node dissection and number of stations.The pulmonary function indexes were compared before and after the operation,and the postoperative complications and survival were observed.Results:Pulmonary segment group patients with thoracic drainage,chest tube indwelling days and hospitalization days were significantly less than lobectomy group,the difference was statistically significant(P<0.05);The number of lymph node dissection in the lobar group was significantly more than that in the pulmonary segment group,and the difference was statistically significant(P<0.05),but there was no significant difference between the number of mediastinal lymph node dissection and the number of stations(P>0.05);the two groups of patients with operation time and intraoperative bleeding had no significant difference(P>0.05),The VAS scores of Id,3d and 7d in the pulmonary segment group were not significantly different from those in the lung group,and there was no significant difference(P>0.05).FVC,FEV1 had no statistical significance in two groups of patients before opreation(P>0.05);after the different surgical treatments,the two groups FVC,FEV1 were significantly lower than the preoperative,the differences were all statistically significant(P<0.05);and the pulmonary segment group of patients after opreation FVC was significantly higher than that of Lung Group(2.88 ±0.46 VS 2.52±0.45),FEV1 was significantly higher than that of lung(83.60±11.56 VS 74.23±10.88),the differences were statistically significant(P<0.05).Postoperative follow-up,pulmonary infection,atelectasis,leakage and other complications occurred in two groups of patients,and there were no significant differences between the two groups(P>0.05)of patients with the complication rate and incidence rate of postoperative complications.Up to date found no tumor recurrence,metastasis and death cases.Conclusion:Compared with minimally invasive lobectomy in the treatment of early GGO type NSCLC,minimally invasive anatomic segmentectomy helps protect the lung function,the recent safety seems to be higher,oncology efficacy,and the complication rate was not significantly increased,minimally invasive anatomic lung resection is the preferred treatment for early GGO type NCSLC...