Clinical Observation On Treatment Of Perimenopasual Syndrome With Chaihu Jia Longgu Muli Decoction And Remifemin

Objective:In this study,Chaihu Jia Longgu Muli Decoction and Remifemin were used to treat perimenopausal syndromes.The clinical efficacy and advantages of the two treatment options were compared to provide more effective and safe drug selection for patients with perimenopausal syndrome.Methods:The patients with perimenopausal syndrome were divided into 30 patients in the treatment group and 30 patients in the control group.The treatment group took Chaihu Jia Longgu Muli Decoction,and the control group took Remifemin.Drug in the two groups were 12 weeks,during this period were observed two groups of patients’treatment of 4 weeks,8 weeks,12 weeks improved library berman index score(KMI)changes and its clinical effectiveness,life quality score(MENQOL)menopause change,related adverse reaction of department of gynaecology,the clinical effect and safety of the two methods are compared.Results:1.Improved Kuperman symptom scores:The total scores of the treatment group decreased significantly at 4 weeks,8 weeks,and 12 weeks(P<0.05).The difference was statistically significant.The total scores of the control group at 8 weeks and 12 weeks were significantly lower than before(P<0.05),and the difference was statistically significant.This shows that both treatment options can effectively improve perimenopausal syndrome.2.Clinical efficiency:The clinical efficacy rate of the treatment group was higher than that of the control group at each time period.The difference between the two groups was statistically significant(P<0.05),indicating that the treatment group had a rapid onset of action and the final efficacy was better than that of the control group.3.MENQOL score:(1)vasomotor and psychological dimensions:the treatment group and the control group improved significantly at 4 weeks,8 weeks ago(P<0.05),and the comparison between the two groups(P all<0.05)Statistically significant,the treatment group was superior to the control group.(2)Physiological dimensions:Both groups began to improve at 8 weeks before(P<0.05),and between the two groups at 12 weeks(P<0.05),the difference was statistically significant,and the curative effect was better than that of the control group.(3)Sexual dimension:The treatment group did not improve after 12 weeks of medication(P>0.05),and the difference was not statistically significant.The control group improved significantly after 12 weeks of treatment compared with before treatment and 4 weeks after treatment(P<0.05),The difference was statistically significant.There was a statistically significant difference between the two groups at 12 weeks(P<0.05),and the control group was superior to the treatment group.Explain that the two groups have different advantages in different dimensions.Conclusion:Both Chaihu Jia Longgu Muli Decoction and Remifemin can safely and effectively improve perimenopausal syndrome and each has its own advantages,among which traditional Chinese medicine has the characteristics of rapid onset and high clinical efficiency.