The Effect Of Thyme Tongxin Dropping Pills On Ventricular Remodeling In Patients With Ischemic Cardiomyopathy Chronic Heart Failure

Research purposeTo study the effect of thyme tongxin dropping pills on ventricular remodeling in patients with chronic heart failure with ischemic cardiomyopathy.The research methodsScreening of patients with chronic heart failure in patients with ischemic cardiomyopathy(1)had been diagnosed during the hospitalization period from June 2016 to June 2017 in hunan people’s hospital.Patients who met the inclusion criteria were randomly divided into two groups:treatment group and observation group.Patients in each group had standardized treatment for chronic heart failure in outpatient follow-up and had completed the drug adjustment.The treatment group was treated with oral thyme tongxin dropping pills 3 times a day,70mg each time.Two groups of patients before into the group,the group after 1 month,3 months and 6 months,during the period,the detection of brain natriuretic peptide(NT-ProBNP),MMP-9(Matrix metalloproteinase 9,MMP-9),galactose lectin-3(Galectin 3,Gal-3),heart colour to exceed the left ventricular end-diastolic diameter,left ventricular end systolic diameter and ejection fraction.Comparison of the differences between the experimental group and the observation group in the same drug time mmp-9,gal-3,the left ventricular diastolic inner diameter of the heart color ultrasound,the left ventricular systolic internal diameter,and the ejection fraction.To determine the influence of musk-tongxin dropping pills on ventricular remodeling.The results of the study1.Compared with the group,the group after 1 month,3 months,6 months,the observation group and treatment group,all the patient’s level of NT-proBNP is into the group fell,the difference is statistically significant(P<0.05),the set of 6 months,the treatment group compared with the observation group,treatment group decreased more significantly,statistically significant difference(P<0.05).2.In the first month of the group and in the group,the mmmmmmmmp-9 has gone down,and the difference is not statistically significant,the difference is not statistically significant,and the difference between the group and the treatment group is that the mmmmmp-9 has decreased in the group,and the difference is statistically significant.Compared with the two groups after June,the level of mmp-9 decreased significantly in the treatment group,and the difference was statistically significant(P<0.05).3.Compared with the group,the group after January and march,group and treatment group Gal-3 levels in patients with decreased,no statistically significant difference(P>0.05),the group after six months,observe group and treatment group pat:ients Gal-3 level is in the group were decreased,statistically significant difference(P<0.05).The level of gal-3 in the treatment group was significantly lower than that between the two groups after June,and the difference was statistically significant(P<0.05).4.Compared with the group,there was no significant difference in the left ventricular diastolic internal diameter of the left ventricle and the left ventricular systole in the two groups after January,march and June,and the difference was not statistically significant(P>0.05).Compared between the two groups after June,there was no statistically significant difference between the left ventricular diastolic and the left ventricular systolic inner diameter(P BBB 0.05).5.Compared with the group,the group 1 month,3 months after the two groups of patients with left ventricular ejection fraction change is not obvious,there was no statistically significant difference(P>0.05),the group of six months,two groups of left ventricular ejection fraction is into the group compared are rising,statistically significant difference(P<0.05).After 6 months in the group,compared between the two groups,the left ventricular ejection fraction treatment group increased significantly,and the difference was statistically significant(P<0.05).The research conclusionMmp-9,gal-3,nt-probnp and LVEF values in patients with chronic heart failure in patients with ischemic cardiomyopathy can be reduced by musk-heart drop pills,which can improve the ventricular remodeling in patients with chronic heart failure.