Analysis Of Neonatal Pathological Jaundice Due To Maternal Factors

Objectives:To analysis the relationship between the occurrence and severity of pathological jaundice in newborns and maternal factors.Methods:It was a hospital based retrospective,non-randomized study conducted at Neonatal Department of Pediatrics in Second Affiliated Hospital of Kunming Medical University.Patients admitted during the period of six months from January 2017 to June 2017 were included.120 cases were enrolled in the study.Data were collected using the newborns medical records and interview sessions with the mothers.A checklist consisting of demographic,neonatal and maternal information.The neonatal information included hospitalization,blood group,laboratory test results.Moreover,maternal information including pregnancy,mother’s age,mother’s blood group,gender,oxytocin induction and mode of delivery were collected.The application of SPSS 22.0 software was used for analysis of single factor and multiple factors<0.05 is statically significant.Results:The total bilirubin levels among newborns delivered normally(288.98μmol/L±75.87μmol/L),caesarean section(250.90μmol/L±72.61μmol/L)and forceps delivery(172.18μmol/L ±99.39μmol/L)were compared and found to be statically significant(p<0.01).The total bilirubin levels among newborns delivered by normal delivery were found to be higher than that of the caesarean section or forceps delivery.The total Bilirubin level among newborns delivered by oxytocin induction(283.83μmol/L ± 79.98μmol/L)was higher than the newborns without oxytocin induction(248.78μmol/L±72.86μmol/L).Statically is(p<0.02).The total bilirubin of the newborns born from mother with age less than 35 years(273.14μmol/L ±81.39μmol/L)and mother with age more than or equal to 35 years(272.11μmol/L ±61.12μmol/L)were compared and was found not to be statically(p>0.05).The total bilirubin levels of the newborn blood type is 0 group(258.18μmol/L ±79.35μmol/L)and A,B,AB blood group is(286.45μmol/L ±77.31μmol/L)were compared and was found to be statically significant(p<0.05).The total bilirubin level among newborns delivered by mother with gestational age of more than 37 weeks,full term(273.38μmol/L ± 79.83μmol/L)and less than or equal to 37 weeks,preterm(259.13μmol/L ±60.48μmol/L)compared and was not found to be statically significant(p>0.05).The mean total bilirubin level among male newborns(287.15μmol/L ±75.12μmol/L)was higher than the female newborns(254.56μmol/L ±81.38μmol/L).Independent t-test result showed a statistically significant(p<0.05).The mean total bilirubin level among newborn feed with breast milk(287.39μmol/L±79.13μmol/L)is higher than that of the mean total bilirubin level among newborn feed with the formula feeding(244.99μmol/L±66.62μmol/L)and mixed milk(254.94μmol/L ±81.41μmol/L).ANOVA test were found statistically significant(p<0.05).Conclusion:Normal delivery,ABO incompatibility,male gender and oxytocin induction and influence the incidence and severity of jaundice in neonates.ABO incompatibility is found as a main leading cause of neonatal jaundice.Maternal age,gestational age-all these factors do not have any association with neonatal hyperbilirubinemia.