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Evaluation Of Left Ventricular Function Changes In Patients With Coronary Heart Disease Before And After PCI Treatment In Coronary Artery Left Anterior Descending Coronary Artery By 3D-STI

Posted on:2019-06-19Degree:MasterType:Thesis
Country:ChinaCandidate:X BaiFull Text:PDF
GTID:2394330566492060Subject:Imaging and nuclear medicine
Abstract/Summary:PDF Full Text Request
Objective : To explore the application of three-dimensional speckle tracking imaging in quantitative evaluation of coronary heart disease patients with left anterior descending coronary artery after percutaneous coronary intervention(PCI)myocardial ischemia segments before and after surgery,indirectly reflect the perfusion of myocardium and to evaluate the left ventricular systolic function changes.Methods:In 30 patients who underwent left anterior descending branch of the PCl in patients with coronary heart disease(research group)were performed before the operation and 3~5days after the operation,3 months later and 30 normal adults(control group)by conventional echocardiography and three-dimensional echocardiography for two patients of conventional echocardiographic parameters of left anterior descending coronary artery myocardial segments,7 segments(basal anterior,basal anterior-septum,mid anterior,mid anterior-septum,apical anterior,apical septum,apex)the systolic longitudinal strain,radial strain,circumferential strain and area strain parameters of each area.Comparative analysis of the changes in patients with coronary heart disease before and after PCI.Results:The routine echocardiographic display:The LVEF of PCI before operation and 3~5days after operation were lower than that in the control group,the LVEDV and LVESV was higher than those in the control group,the difference was statistically significant(P<0.05).There was no significant difference in LVEDV,LVESV and LVEF between 3 months after PCI and the control group,with no significant difference(P > 0.05).There was no significant difference in LVEDV,LVESV and LVEF between 3~5 days after PCI and that before operation,the difference was not statistically significant(P > 0.05).LVEDV and LVESV decreased and LVEF increased after 3 months,compared with preoperative and postoperative3~5 days the difference was statistically significant(P<0.05).The three-dimensional echocardiographic display : The study group(before the operation,3~5 days after the operation,3 months after the operation)left anterior descending artery 7 myocardial segments(basal anterior,basal anterior-septum,mid anterior,mid anterior-septum,apical anterior,apical septum,apex)of LS,AS,CS,RS were lower than the corresponding control group of myocardial segments,the difference was statistically significant(P < 0.05).PCI 3~5 days after operation compared with the preoperative 5 segmental longitudinal strain(basal anterior,basal anterior-septum,mid anterior,mid anterior-septum,apical anterior),3segmental circumferential strain(basal anterior,basal anterior-septum,mid anterior),3segmental area strain(basal anterior,mid anterior,mid anterior-septum)and 2 segmental radial strain,basal anterior-septum,mid anterior)increased,the difference was statistically significant(P < 0.05);3 months after surgery,the strain parameters were significantly higher than those before and after 3~5 days,the difference was statistically significant(P < 0.05).Conclusions:The three-dimensional speckle tracking imaging can detect the changes of left ventricular regional systolic function in patients with coronary artery after PCI in left anterior descending coronary artery disease,and evaluate myocardial function quantitatively,so as to provide a theoretical basis for clinical evaluation of PCI outcome and subsequent treatment.
Keywords/Search Tags:Coronary heart disease, speckle tracking imaging, coronary stent implantation, ultrasound examination
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