The Contrast Between The Early Abortion Patients With Recurrent Spontaneous Abortion And The General Patients In TCM Syndromes,Coagulation Function And Pregnancy Pressure

Objective : To explore whether there were differences of TCM syndrome type distribution,coagulation correlation index,the degree of anxiety and depression and pregnancy stress between threatened abortion patients with/without a history of RSA and their respective characteristics.It was expected to provide a basis for clinical diagnosis and treatment,identify the risk of abortion as early as possible,and avoid the development of threatened abortion to RSA.Method: After consulting the relevant information,the diagnostic criteria,the inclusion criteria and the exclusion criteria were formulated and the questionnaire was designed by ourselves.According to the history of RSA and divided into two groups,using the self-designed " general situation Questionnaire",Zung’s "SAS" and "SDS," Chen Zhanghui compiled the "pregnancy stress scale" questionnaire.The results of the survey were entered into Excel and SPSS 22 to establish the database,and the statistical analysis was performed.Statistical methods were used as follows:frequency analysis;the mean number value plus or minus standard deviation;t test;nonparametric rank sum test;chi square test.Results:(1)A total of 233 questionnaires were collected from the Department of gynecology inpatient department of Chengdu University of Traditional Chinese Medicine Affiliated Hospital from February 2017 to February 2018.A total of 233 questionnaires were issued.A total of 220 questionnaires were sent out,and the effective recovery rate of the questionnaire was 94.4%.There was no statistical difference between the two groups in age,educational level,BMI,residence,job stress,monthly income and menstruation(P>0.05).The rate of pre pregnancy physical examination in group B was higher than that in A group,the difference was statistically significant(P<0.05),and the number of dysmenorrhea in group A was higher than that in group B,and the difference was statistically significant(P<0.05).(2)The distribution of TCM syndromes in group B was as follows:kidney deficiency syndrome>kidney deficiency blood stasis syndrome>spleen kidney deficiency syndrome> kidney deficiency and stagnation of liver syndrome>kidney deficiency and blood heat syndrome>spleen and stomach weakness,liver and spleen disharmony syndrome.The distribution of TCM syndromes of group A was as follows: kidney deficiency syndrome > spleen kidney deficiency syndrome > kidney deficiency and stagnation of liver syndrome>kidney deficiency blood stasis syndrome > spleen and stomach weakness,liver and spleen disharmony syndrome >kidney deficiency and blood heat syndrome.The differences in the distribution of the two groups were statistically significant(P<0.05).(3)Compared with the two groups of coagulation indexes,D-D in group B was higher than group A,and the difference was statistically significant(P<0.05).There was no statistically significant difference in PT,APTT,FIB,TT,and PLT(P>0.05).(4)The difference of anxiety in the two groups was statistically significant(P<0.05).There was no significant difference in the degree of depression between the two groups(P>0.05).(5)The two groups of pregnancy stress were all at a mild level,and there was no significant difference(P>0.05).Conclusions:(1)The TCM syndromes of patients with history of RSA were: kidney deficiency syndrome,kidney deficiency blood stasis syndrome,spleen kidney deficiency syndrome,kidney deficiency and stagnation of liver syndrome,kidney deficiency and blood heat syndrome,spleen and stomach weakness,liver and spleen disharmony syndrome.The distribution of TCM syndromes of common precursory abortion was:kidney deficiency syndrome,spleen kidney deficiency syndrome,kidney deficiency and stagnation of liver syndrome,kidney deficiency blood stasis syndrome,spleen and stomach weakness,liver and spleen disharmony syndrome,kidney deficiency and blood heat syndrome.(2)D-D has important clinical value for early identification and diagnosis of RSA.(3)Patients with a history of RSA were more anxious.(4)The distribution of the degree of pregnancy stress in patients with threatened abortion was generally at the level of mild stress.