| Objective:In this study,we observed the changes in the scores of the Berlin Sleep Quality Assessment Questionnaire,Epworth Sleepiness Scale,and TCM Clinical Symptom Score before and after treatment,and evaluated the clinical symptomatic effects of Chinese Herbal Medicine Sputum Treatment for obstructive sleep apnea syndrome.And to explore its correlation with serum inflammatory factors(TNF-a,IL-6)indicators for Chinese medicine in the treatment of obstructive sleep apnea syndrome provides a reference basis.Method:Patients with obstructive sleep apnea syndrome with reciprocal obstruction were randomly divided into treatment group and control group with 36 cases each.The treatment group was given general treatment(as far as possible to take a lateral position and avoid sleeping aids before going to bed.,such as sedatives,to avoid excessive fatigue)+ Chinese medicine treatment,the control group to general treatment,after 12 weeks of treatment,observe the changes of the Berlin sleep quality assessment questionnaire,Epworth sleepiness scale and clinical symptom scores before and after treatment,monitor two groups of TNF-Changes in the index of a,IL-6 to achieve a clear clinical curative effect in the improvement of symptoms of obstructive sleep apnea syndrome.Result:Body mass index(BMI):There was no significant difference between the two groups within and between groups(P>0.05).TNF-a:Intragroup comparison:The difference between the treatment group and the treatment group was statistically significant(P<0.05).There was no significant difference between the control group and the control group before and after treatment(P>0.05);between the groups:after the treatment,the two groups were compared.The difference was statistically significant(P<0.05).IL-6:Comparison within the group:The difference between the treatment group and the treatament group was statistically significant(P<0.05).There was no significant difference between the control group and the control group before and after the treatment(P>0.05);between the groups:after the treatment,the two groups were compared.The difference was statistically significant(P<0.05).Berlin Sleep Quality Assessment Questionnaire:Intra-group comparisons:There was a statistically significant difference between the treatment group and the pre-and post-treatment groups(P<0.05).There was no statistically significant difference between the control group and the pre-treatment group(P>0.05).There was a statistically significant difference between the two groups(P<0.05).Epworth Sleepiness Scale:Intra-group comparison:The difference between the treatment group and the treatment group was statistically significant(P<0.05).There was no significant difference between the control group and the pre-treatment group(P>O.05);between the groups:There was a statistically significant difference between the groups(P<0.05).Clinical symptom scores of TCM:There was a statistically significant difference between the treatment group before and after the treatment in the total score of the TCM syndrome score scale(P<0.05),and there was no statistical difference between the control group before and after the treatment in the total score of the TCM syndrome score scale.Significance(P>0.05).In the single item,the scores of snoring,daytime sleepiness,and morning drowsiness in the treatment group were significantly different before and after treatment(P<0.05),but there was no significant difference in memory and early morning dryness.Statistically significant(P>0.05),there was no significant difference in the five symptom scores of the control group before and after treatment(P>0.05).Conclusion:1.Chinese Herbal medicine can improve the clinical symptoms of obstructive sleep apnea syndrome patients.2.Chinese Herbal Medicine can reduce the levels of serum inflammatory cytokines TNF-a and IL-6 in patients with obstructive sleep apnea syndrome and reduce the scores of the Berlin Sleep Quality Assessment Questionnaire and Epworth Sleepiness Scale.The combined type obstructive sleep apnea syndrome has a good effect. |