Clinical Analysis Of Risk Factors For Liver Failure After Hepatectomy In Patients With Primary Liver Cancer

Objective:To investigate the risk factors of liver failure after hepatectomy in patients with primary liver cancer.Methods:Through retrospective analysis of the Department of hepatobiliary surgery of the Affiliated Hospital of Kunming Medical University,93 cases of primary liver cancer confirmed by hepatectomy from January 2012-December 2017 were reviewed.SPSS21.0 was used to analyze univariate and multivariate analysis of collected data.Results:In 93 cases of hepatectomy for primary liver cancer,20 cases had postoperative liver failure,the incidence rate was 21.51%.Single factor analysis found that ICG-R15(>10%),Child-Pugh grade of liver function(Grade B),tumor size(>10cm),blood loss volume(>1000ml),combined tumor thrombus(portal vein or bile vessel),the number of excision segments(more than three segments),and operation time(>240min)were related to postoperative liver failure.Logistic regression analysis showed that Child-Pugh grade of liver function(grade B),tumor size(>10cm),number of excised segments(more than three segments)and the operation time(>240min)were independent risk factors for postoperative liver failure.Conclusions:1、The liver failure after hepatectomy was related to ICG-R15,Child-Pugh grade of liver function,tumor size,blood loss volume,combined tumor thrombus,number of resection segments,and operation time.2、The independent risk factors of liver failure after hepatectomy for primary liver cancer can be evaluated by Logistic regression analysis,Child-Pugh grade of liver function,tumer size,number of excised segments and the operation time.