Analysis Of The Related Factors Of Residual Or Recurrent Lesions In Patients With Cervical Squamous Intraepithelial Lesions After Surgery

Objective:To investigate the risk factors of residual or recurrence in patients with cervical squamous intraepithelial lesion(SIL)after conical cervical resection.Methods: A total of 281 SIL patients from January 2014 to December 2017 in people’s hospital of guangxi zhuang autonomous region were selected as the study subjects.All patients were hospitalized for cervical conical resection,and standardized follow-up was conducted after the operation.Relevant influencing factors of patients found residual or recurrent were retrospectively analyzed.Results: Retrospective analysis of 281 patients showed that postoperative residual lesions were found in 30 patients during follow-up,and the results showed that age,menopause,HPV infection,viral load and postoperative residual lesions were significantly correlated(P < 0.05).During the follow-up,23 patients were found to have postoperative disease recurrence.Univariateanalysis showed that HPV infection,viral load,and status of the cutting edge were the possible risk factors for postoperative recurrence(P < 0.05).Conclusion :(1)Age,postmenopausal status,HPV infection and viral load were the influencing factors of SIL postoperative residual.(2)HPV infection,viral load and the status of the cutting edge are high risk factors for recurrence after SIL;(3)HPV infection and viral load are independent risk factors for the occurrence,development and recurrence of SIL in patients after cervical cone resection,and HPV genotype is significantly correlated with persistent HPV infection.Therefore,close monitoring of HPV and viral load is of early warning significance for the development of the disease.