Correlation Analysis Between UPOINT Classification Factor And Sexual Dysfunction In Patients With CP/CPPS

Objective To investigate the correlation between UPOINT classification factors and premature ejaculation and erectile dysfunction in patients with chronic prostatitis/ chronic pelvic pian sydrome(CP/CPPS).Methods From December 2016 to December 2017,a total of 453 CP/CPPS patients’ medical history data were collected.The contents included: height,weight,place of birth,occupation,fertility status,income status,education level,behavior and lifestyle,sexual life history,related symptoms and history of prostatitis,prostate ultrasound,digital rectal examination,urine routine,prostatic fluid routine,semen routine,secondary sexual and external genital examination,Rigiscan penis detector,nocturnal penile tumescence functional assessment(NPT),Self-rating Depression Scale(SDS),intra-vaginal ejaculation latency time(IELT),penile sensitivity measurement,National Institutes of Health Chronic Prostatitis Symptom Index(NIH-CPSI),Premature ejaculation diagnostic tool(PEDT),The International Index of Erectile Function(IIEF-5),etc.All patients were classified according to the UPOINT classification system.All questionnaires were filled out by the respondents under the guidance of the researchers in combination with their own situation and medical history.For those with lower education,the researchers explained in detail and filled in according to the facts of the respondents.The relevant research data was reviewed and entered through EPIDATA 3.1 software double-double.The data review mainly included data validity and integrity,and then analyzed by SPSS 13.0 software package.The mean of the relevant data is expressed as ?x±s,and the chi-square test is mainly applied to the comparison of data between groups.Correlation analysis between the two groups was performed using Pearson and Spearman correlation analysis.P < 0.05 difference was statistically significant.Results A total of 453 patients with CP/CPPS were included in the study,with an average age of 32.75 ± 6.85 years(18 to 55 years).The average duration of the disease was 17.23 ± 8.32 months(2 to 62 months).The mean IELT,NIH-CPSI and IIEF-5 were 2.05 ± 0.72 minutes,22.72 ± 5.08 and 20.25 ± 5.12,respectively.According to the diagnostic criteria for erectile dysfunction and premature ejaculation,a total of 204 patients were diagnosed with erectile dysfunction,the prevalence of ED was 45.03%(204/453),and 196 patients were diagnosed with premature ejaculation.The prevalence of PE was 43.27%.(196/453).UPOINT classification factor: A total of 312 cases were diagnosed as urinary symptoms(Urinary,U)68.78%(312/453);a total of 273 cases were diagnosed as psychosocial abnormalities(Psychosocial,P)60.21%(273/453);a total of 351 cases was diagnosed with organspecific(Organspecific,O)77.45%(351/453);a total of 92 patients were diagnosed with infection(Infection,I)20.34%(92/453);a total of 212 patients were diagnosed with neurological/systemic(Neurological/systemic,N)46.83%(212/453);a total of 295 patients were diagnosed with tenderness(Tenderness,T)65.12%(295/453).Among the UPOINT classification factors,psychosocial abnormality P is a risk factor for the onset of PE and ED.Other factors include urinary symptoms(U),organspecific(O),infection(I),neurological/systemic(N),and tenderness(T)is not an independent risk factor for PE and ED.Conclusion The psychosocial(P)in the UPOINT classification system of CP/CPPS patients plays an important role in the pathogenesis of PE and ED.