Study On The Distribution Of Syndrome Differentiation Of Six Meridians In Rheumatoid Arthritis

ObjectiveThe distribution of six meridian syndromes of rheumatoid arthritis was analyzed from six meridians syndrome differentiation and clinical observation,and the relationship between the three yin and three yang meridians syndromes and different conditions,condition,course of disease and related laboratory indexes of rheumatoid arthritis was studied.MethodsThis subject collects and investigates the clinical data of 238 patients with rheumatoid arthritis by retrospective research method,including sex,age,course of disease,information of four diagnostic methods of traditional Chinese medicine,relevant physical and chemical indexes such as ESR,C-reactive protein,rheumatoid factor,anti-cyclic peptide containing citrulline,hemoglobin,and so on.The distribution of six meridian syndromes in patients with rheumatoid arthritis was analyzed by statistical analysis to explore the correlation between six meridian syndromes and various indicators.Results1.238 RA patients had 15 six meridian syndromes,6 single meridian syndromes and 9 syndromes.Among the 15 six meridian syndromes,Taiyin disease was the most common,accounting for 23.5%,followed by Shaoyang disease(14.7%),Shaoyin disease(11.8%),Shaoyang-Taiyin syndromes(10.1%).Shaoyang-Taiyin disease was the most common syndromes of the two syndromes,accounting for 24 cases(10.09%).The symptoms of RA patients are more complex.The frequency of symptoms in RA patients is joint pain,morning stiffness,cold fear,joint fever,stomach discomfort,fecal rot,cold limbs and bitter mouth.In the aspect of tongue vein,the most common tongue image is tender and white tongue,and the most common pulse image is weak pulse.2.Statistics show that the highest frequency of each meridian disease is Taiyin disease,accounting for 40.3%,followed by Shaoyang disease,accounting for 33.2%,calculated by golden section method,40.30%+33.2%>61.8%.It can be seen that the main syndrome differentiation types of patients are Taiyin disease and Shaoyang disease.The incidence of Yangming disease was the lowest,accounting for 6.7%.3.To study the relationship between sex,age,course of disease and the commonly used laboratory indicators of RA,such as ESR,ACCP,RF,CRP,HGB and six meridian syndromes.According to the analysis,there is no significant difference in the value distribution of ACCP between the six meridian syndromes,indicating that the specific antibody ACCP of RA does not affect the formation of the six meridian syndromes.In the other clinical indicators,there are significant differences among the six meridian syndrome groups,which may affect the formation of the six meridian syndrome.ConclusionThe ratio of male to female in this study is 1:3.67,which is basically in line with previous studies.Age of onset,41-60 years old is the main population of RA.The number of patients with a course of 0-5 years is the largest.This may be related to the factors such as the time of each visit gradually prolonged after the patients were diagnosed with RA.The most common symptoms were joint pain,morning stiffness,fear of cold,joint fever,stomach discomfort,rotten stool,cold limbs and bitter mouth.The most common tongue image is tender and white tongue,and the most common pulse image is weak pulse.The frequency of Taiyin disease and Shaoyang disease is the highest in the distribution of the syndromes of the six meridians.Gender,age and course of disease may affect the formation of six meridians syndrome.Compared with the laboratory indexes of each syndrome group,the inflammatory indexes ESR and CRP have significant differences among different syndrome types,indicating that the level of ESR and CRP may affect the formation of six meridians syndrome.There are significant differences in the distribution of RF in different syndromes.It shows that the level of RF affects the formation of six meridian syndromes.