Clinical Application Of Ultrasound-guided Ropivacaine Combined With Dexmedetomidine Anterior Serratus Plane Block In Modified Radical Mastectomy For Breast Cancer

Objective:To analyze the effect of ultrasound-guided ropivacaine complx dexmedetomidine anterior serratus plane block in modified radical mastectomy for breast cancer..Methods:Prospectively selected 90 patients with modified radical mastectomy were randomly divided into 3 groups by random number method: group A: control group;group B: ultrasound-guided ropivacaine anterior serratus plane resistance Stagnation group;group C: ultrasound-guided ropivacaine complex dexmedetomidine anterior serratus plane block group.Record the intraoperative dose of remifentanil,propofol and 24-hour postoperative use of sufentanil,and record the number of effective ammonium pressures,extubation time and PACU residence time of the analgesic pump;observe and record T1(Immediately after extubation),T2(out of PACU time),T3(2h after extubation),T4(4h after extubation),T5(8h after extubation),T6(12h after extubation),T7(after extubation)24h)Visual analogue(VAS)score,statistical control of analgesia pump compression times,analgesic remediation and adverse reactions.Results:1.The results showed that the amount of medium and long-chain propofol in group B and C was significantly lower than that in group A(P<0.05).The dose of remifentanil in group B and C was significantly lower than that in group A.The difference was significant(P<0.05).There was no significant difference in the amount of propofol and remifentanil in group C compared with group B(P>0.05).Compared with group A,tracheal extraction time was significantly shorter in group B and C than in group A(P<0.05).There was no significant difference in PACU residence time between the three groups(P>0.05).2.Within 24 hours after extubation,the VAS scores of the B group and the Agroup were significantly decreased during the period from T1 to T4(P<0.05);the C group was compared with the A group during the T1~T7 period.The VAS scores were significantly lower(P<0.05).There was no significant difference in the VAS scores between the B group and the C group during the T1~T4 period(P>0.05).At the T5 and T6 points,the C group and the B group The VAS scores were significantly different(P<0.05).The VAS scores in group C were significantly lower than those in group B.At T7,the VAS scores of the three groups were similar.(P>0.05).3.The effective compression times of postoperative analgesia pump and the dose of sufentanil after operation in group C were lower than those in group A and B(P<0.05).In group A,there were 7 cases of postoperative complications and 2 cases of nausea in group B.There were no significant dose-dependent side effects of Dex in Group C.Conclusion:Preoperative ultrasound-guided ropivacaine combined with dexmedetomidine anterior serratus plane block can prolong the time course of effective analgesia and reduce the total consumption of postoperative systemic opioids without increasing In the case of post-complication,the quality of rehabilitation is improved,which is better than the simple ropivacaine anterior serratus plane block.