Analysis Of Urinary Calculi Composition And Related Risk Factors Of Hui Nationality In Xining Area

Objectives To analyze the distribution characteristics of urinary calculi in Hui nationality in Xining,and to explore the relationship between the formation of urinary calculi in Hui nationality and diet,living habits and metabolism,and to provide a more accurate basis for the prevention and treatment of urinary calculi in Hui nationality in Xining.Methods A total of 150 patients with urinary calculi who were hospitalized in the Department of Urology,Qinghai Provincial People’s Hospital from January 2017 to January 2019 were enrolled.A total of 183 cases with non-urinary calculi in the same period were included in the control group.The stone specimens of the case group were collected,and the infrared spectroscopy analysis were used for the stone specimens.Blood samples were collected from the case group and the control group to measure the triglyceride,total cholesterol,blood uric acid,blood sugar and blood calcium.24-hour urine samples were collected to measure urine volume,urinary calcium,urinary potassium,urine sodium,urine chlorine,Urine phosphorus and urinary magnesium.A questionnaire survey was conducted on the case group and the control group.Results 1.The proportion of male and female patients with urinary calculi in the Xining area was 1.88:1.The 40-55 age group accounted for the highest proportion,and the rural residents accounted for the highest proportion.2.The detected urinary stones were mainly mixed stones,and the calcium oxalate stones were the most.The detections of four main types of stones were not statistically significant different in genders(P>0.05).3.The detection of magnesium ammonium phosphate stones was statistically significant in diverse age groups of different genders(P<0.05).The detections of other types of stones were not statistically significant in diverse age groups of different genders(P>0.05).4.The detected urinary calculi mostly were upper urinary tract stones,and the upper urinary tract stones were mainly composed of calcium oxalate and calcium phosphate stones.5.10 factors were screened out which affect the formation of urinary stones,including the urine volume,urinary calcium,urinary magnesium,BMI,drinking water,tea,beef and mutton,animal offal,activity and family history of urinary stones.Multi-factor analysis results showed that the four factors were independent risk factors,which were high urinary calcium(OR=2.770,95% CI: 1.621~4.731)and high BMI(OR= 1.865,95% CI: 1.219~2.854),eating more animal offals(OR=1.540,95% CI: 1.064~2.228)and family history of urinary stones(OR=4.315,95% CI: 1.952~9.538);The factors were independent protection factors,including drinking tea(OR=0.704,95% CI: 0.514~0.965)and activity(OR=0.605,95% CI: 0.379~0.965).Conclusion The detection rates of magnesium ammonium phosphate and uric acid stones in Hui patients in Xining area are more than the multi-regional average in the country.Factors such as metabolism,diet,lifestyle and family history of Hui people in Xining have an impact on the formation of urinary stones.