Study On Risk Factors Of Progressive Cerebral Infarction In Han And Tibetan In Xining Area

Objectives To investigate the incidence and risk factors of Progressive Cerebral Infarction(PCI)in Han and Tibetan ethnic groups in Xining area.Methods Continuously included in the Xining District of Qinghai Province(2,260meters above sea level,who has lived in Xining for more than 10 years)in the Department of Neurology,Qinghai Provincial People’s Hospital,Qinghai Provincial Tibetan Hospital,and the First People’s Hospital of Xining City from March 2016 to March 2017.Han,Tibetan cerebral infarction patients,a total of 634 cases.Among them,370 were Han Chinese and 264 were Tibetan.According to the National Institutes of Health Stroke Scale(NIHSS)score,the Chinese and Tibetan cerebral infarction groups were divided into Han Chinese PCI group and Non-progressive cerebral infarction group(NPCI).Tibetan PCI group and Tibetan NPCI group.To calculate the prevalence of PCI in Han and Tibetan ethnic groups and analyze the risk factors of PCI in Han and Tibetan populations.Results Of the 634 patients with cerebral infarction,140 were Han PCI(37.8%of cerebral infarction in Han),78 were Tibetan PCI(29.5%of cerebral infarction in Tibetan),and the proportion of Han in Han population was higher than that in Tibetan(X~2=4.696).P<0.05).Multivariate logistic regression was performed by Han and Tibetan populations separately:NIHSS scores on admission were>10 points(odds ratio,OR 5.460,95%confidence interval,95%CI,3.250 to 9.171,p=0.000),elevated body temperature(OR 2.457,95%CI,1.448 to 4.168,p=0.001),positive rate of cervical plaque(OR 1.908,95%CI,1.134 to 3.211,p=0.015),hyperglycemia(OR3.395,95%CI,2.004-5.753,p=0.000),and high C-reactive proteinemia(OR 1.806,95%CI,1.098-2.969,p=0.020)were independent risk factors for the development of cerebral infarction in Han Chinese.NIHSS score>10 points(OR 4.167,95%CI,2.253 to 7.709,p=0.000),increased body temperature(OR 2.431,95%CI,1.268 to4.660,p=0.007),and positive rate of cervical plaque on admission(OR 2.547,95%CI,1.386 to 4.681,p=0.003),hyperglycemia(OR 2.833,95%CI,1.531 to 5.240,p=0.001),and systolic blood pressure decreased after admission(OR 2.251,95%CI,1.088～4.657,p=0.029)is an independent risk factor for the development of cerebral infarction in Tibetans.The Chinese and Tibetan PCIs have the same distribution of the responsible blood vessels,and both of them have been predominantly circulating.There was no significant difference between the two groups in the Han and Tibetan PCI(X~2=2.457,P>0.05).Conclusions The incidence of PCI in the Han nationality in Xining is higher than that of Tibetans.NIHSS score>10 points,elevated body temperature,positive rate of cervical plaque,and hyperglycemia were common risk factors for PCI in Han and Tibetan cerebral infarction patients.However,the Hans are also associated with high C-reactive proteinemia,and Tibetans are also associated with decreased systolic blood pressure after admission.The distribution of the responsibility blood vessels of the Han and Tibetan PCI is the same,and both of them are predominantly circular.