Clinical Observation On Treatment Of Allergic Cough With Syndrome Of Wind-heat Invading Lung In Children By Eliminating Wind For Relieving Spasm

Objective:The purpose of this study is to summarize and explain the clinical effect of wind-calming spasmolytic therapy on allergic cough in children by observing the changes of indexes such as main symptoms and secondary symptoms of allergic cough(syndrome of wind-heat invading the lung)after intervention of wind-calming spasmolytic therapy,so as to provide reference for enriching the traditional Chinese medicine and clinical treatment of this disease with wind-calming spasmolytic therapy.Method:From December 2017 to December 2018,60 cases of children who met the criteria of western medicine diagnosis for children allergic cough and the criteria of traditional Chinese medicine syndrome differentiation for wind-heat invading lung syndrome in this research plan were selected from the pediatric outpatient department of the Affiliated Hospital of Gansu University of Traditional Chinese Medicine.60 qualified cases were collected according to the inclusion and exclusion criteria as subjects and divided into treatment group and control group with 30 cases in each group according to the random number table method.Among them,30 cases in the treatment group were treated with traditional Chinese medicine decoction-free granules,while the control group was treated with Xiaoer Feire Kechuan Oral Liquid.General data records were completed on the first day after entering the group.The improvement of symptoms in the two groups were observed before treatment and on the 7th and 14 th days after treatment.Quantitative scores were made for the changes before and after the main symptoms and secondary symptoms in the two groups respectively.SPSS21.0software was used for statistical analysis after the above data were recorded and sorted out,so as to summarize their clinical characteristics and evaluate their efficacy.Result:1.Efficacy analysis(1)Total effective rate:(1)Treatment group:14 cases were clinically cured(46.7%),16 cases were markedly effective(53.3%),and the total effective rate was 100%;(2)Control group:no clinically cured cases,6 cases were markedly effective(20%),23 cases were effective(76.7%),1 case was ineffective(3.3%),and the total effective rate was 96.7%.After statistical analysis,the difference was statistically significant(P<0.05).(2)TCM syndrome curative effect,TCM syndrome total score and disease degree change:the difference between the two groups and within each group has significant statistical significance(P<0.05).(3)Symptom score:(1)main symptom score:the difference between the treatment group and the control group was statistically significant(P<0.01),while the control group showed significant difference(P<0.05).After treatment,the difference between the two groups was statistically significant(P<0.05).(2)Secondary symptom score:There was no significant difference between the two groups before and after treatment(P>0.05).The difference was statistically significant in the treatment of sub-symptoms of pharyngeal itching,pharyngeal redness,nasal congestion,nasal itching and anorexia(P<0.05).There was no significant difference between the two groups in the treatment of hypopharyngeal dryness,sneezing,abdominal distension and dry stool(P>0.05).2.Safety analysis during follow-up treatmentIn the two groups,5 children suffered from loose stool within 2 weeks after taking the medicine,which was obvious in the control group(3 cases),but all recovered to normal stool after stopping taking the medicine,which was a normal pharmacodynamic response after taking the medicine.No obvious adverse reactions occurred in the two groups during treatment.Conclusion:(1)The pathogenic wind is the inducement of allergic cough in children,“latent pathogen” is the root of the disease,and “spasmodic cough” is the standard symptom of the disease.Wind-heat invasion of lung is common during the attack period,and the treatment of wind-heat is mainly based on the analysis of the causes of stopping wind and spasm,and the treatment of wind drugs.(2)The method of eliminating the wind for relieving spasm has definite curative effect on infantile allergic cough(syndrome of wind-heat invading the lung),can effectively and timely control symptoms,has remarkable effect on improving spasm cough,which is a major symptom.