| Objective:Through the retrospective analysis of 328 cases of Acute pancreatitis(Acute pancreatitis,AP)in patients with clinical cases,analysis the AP etiology and causes and age,sex,seasonal factors,such as correlation,the patient summary AP pathogenesis regularity,to guide the clinical treatment of AP,improve prognosis and to prevent recurrence.Methods:A total of 328 AP patients admitted to the first affiliated hospital of wannan medical college from September 2017 to September 2019 were selected to meet the inclusion and exclusion criteria.The patient’s gender,age,occupation,admission time,cause of illness,length of stay,complications and complications were recorded.SPSS22.0 software was used to calculate the relevant data.The measurement data were expressed asx?sand compared with t test.(%)was used as enumeration data,2 test and Fish exact probability test were carried out.Kruskal-wallish test was used for comparison among multiple groups.If P < 0.05 was obtained,the comparison showed statistical difference.Results: A total of 328 AP cases were included,including 178 males(54.3%)and 150females(45.7%),with a male-to-female ratio of 1.18:1.The age range is 15-92 years old,with an average age of 54.14±17.11 years old,202 people(61.6%)who are ≤60 years old,and 126 people(38.4%)who are 60 years old.There are 121 people(36.9%)in analytical and freelance occupations,81 farmers(24.7%),44 workers(13.4%),25individuals(7.6%),30 retired workers(9.2%),19 staff(5.8%),and 8 students(2.4%).According to the etiology can be divided into biliary,lipid,alcohol,tumor related,other etiology(drugs,infection,surgery,etc.)and unknown etiology.Among them,179(54.57%)were biliary,52(15.85%)were lipogenic,50(15.24%)were alcoholic,15(4.57%)were tumor-related,6(1.8%)were of other etiology(drugs,infection,surgery,etc.),and 26(7.9%)were of unknown etiology.Etiology and gender relations: the male 178 cases,of which 84 cases(47.2%)of the gallstone,fat source sex in 31 cases(17.4%),alcoholic in 36 cases(20.3%),tumor in 10 cases(5.6%),the other13 patients(7.3%)and unknown etiology in 4 cases(2.2%).150 cases of women,which in 95 patients(63.4%)of the gallstone,fat source sex in 31 cases(14%),alcoholic in 14cases(9.4%),tumor in 5 cases(3.3%),and other 13 cases(8.6%),Two patients(1.3%)had unknown etiology.There was a statistical difference in the distribution of gallbladder and alcoholic pancreatic sex between male and female(x2=8.556,p<0.01).X2 = 7.474,p < 0.001).Etiology and age:Elderly group 202 cases,of which 88 cases(43.6%)of the gallstone,fat source sex of 50 cases(24.8%),alcoholic41 cases(20.3%),tumor in 6 cases(3%)and unknown etiology in 1 case(0.5%),and other 16 cases(7.9%).The elderly group of 126 cases with gallstone in 91 patients(72.2%),fat source sex have 2 cases(1.59%),alcohol has 9 cases(7.1%),tumor 9 cases(7.1%)and unknown etiology in 5 cases(4.0%),other 10 cases(8%).The elderly group gallstone is notably higher than that of non elderly group,However,in terms of lipid and alcohol,it was significantly lower than that of the non-elderly group,with statistically significant differences(x2=25.707,p<0.01).X2 = 31.214,p < 0.001;X2 = 10.372,p <0.001).The relationship between etiology and disease severity: 273 cases were non-severe,55 cases were severe,and the proportion of biliary non-severe group was significantly higher than that of the severe group,with statistically significant differences(x2=21.068,p<0.01).There was no correlation between etiology and season and length of stay.Of the 328 cases,137(41.8%)had comorbidity,among which 103(31.4%)had one comorbidity,30(9.1%)had two comorbidity and 4(1.3%)had threecomorbidity.Complications occurred in 57(17.4%)of the 328 cases,including 47(14.3%)of one complication and 10(3%)of two complications.Conclusion: 1.Biliary tract disease is still the primary cause of clinical acute pancreatitis,and the proportion of hyperlipidemia and alcohol-related factors has increased.2.Biliary pancreatitis is more likely to occur in the elderly,while lipid and alcoholic pancreatitis are more likely to occur in the young;The incidence of biliary pancreatitis was mainly in females,and the incidence of alcoholic pancreatitis was higher in males than in females.3.Biliary pancreatitis are often relatively mild to moderate. |