| ObjectiveTo study the effect and clinical efficacy of the injection of pituitrin in patients with uterine myoma.The surgical procedures included laparoscopic myomectomy and abdominal myomectomy.MethodsThe case is from heze municipal hospital in 2017,120 cases of myomectomy coorresponding to diagnosis standards were performed in our hospital found by gynecological B-ultrasonography of uterine myoma,including 60 cases of TAM and 60 cases of LM.All cases did TCT examination before operation in order to rule out cervical cancer.Uterine myoma which had been found for a long time could lead to irregular menstruation,so the diagnostic curettage should be performed to rule out endometrial lesions.Not only patients with liver and kidney dysfunction but also these with severe organ diseases and coagulation disorders should be excluded at the same time.All the rapid pathological examinations during the operation were uterine myoma.The 60 patients in LM group were randomly divided into two groups : C1 group local injection of pituitrin LM30 cases;C2 group did not use pituitrin LM30 cases,while the 60 patients in TAM group were randomly divided into two groups: D1 group using pituitrin TAM 30 cases;D2 group did not use pituitrin TAM 30 cases.The same doctor did all the operations.Postoperativepatients were treated with the same anti-infective and nutritional support,and the catheter was removed on the second day after surgery.In the C1 D1 group,pituitrin was injected in the myometrium muscle layer and pituitrin 6 IU was diluted into 20 ml 0.9% NS.The pituitary vasopressin was not given in the C2 D2 group.We analyzed the mean operation time,intraoperative blood loss,blood pressure changes after treatment,average length of hospital stay,postoperative average anus exhaust time,and changes in blood routine of the patients in these groups.All the 60 patients in the LM group were successfully completed without changing into transabdominal operation.ResultsThe average time needed for surgery in the C1D1 group was significantly shorter than that in the C2D2 group(P<0.05),difference makes sense.The average intraoperative blood loss in C1 D1 group was less than that in the C2D2 group(P<0.05)with statistical significance.In the C1 D1 group,the blood pressure increased significantly(P<0.05)at 15 min and 30 min after administration.After 60 min,the blood pressure of the patients gradually recovered,but there was no significant change in the C2 D2 blood pressure value;C1 D1 group surgery after the average anus exhaust time and average length of stay and C2 D2 group average postoperative anal exhaust time and there was no significant difference between the average days of hospitalization(P>0.05)and no statistical meaning;Hemoglobin in C1D1 group shows higher level than the C2D2 group(P< 0.05)which was statistically meaning.ConclusionsHysteromyoma removal using pituitrin can reduce intraoperative blood loss and shorten the operation time in both laparoscopic surgery and laparotomy.Postoperative rehabilitation is faster,which is worthy of the promotion and application of gynecologists.MeaningThere will be more bleeding in myomectomy owing to the abundant uterine blood supply and large wounds.So the hemostasis during surgery becomes more difficult.It is very important to shorten the operation time and reduce blood loss during the surgery.Therefore,the purpose of this study was to discuss the effect of pituitrin on laparoscopic uterine myomectomy and abdominal myomectomy in relation to the amount of bleeding and clinical efficacy,and to provide relevant clinical evidence for the hemostatic method for female hysteromyoma elimination. |
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