Correlation Between 25-hydroxyvitamin D Levels And Metabolic Syndrome In Patients With Type 2 Diabetes

Objective:To investigate the relationship between 25-hydroxyvitamin D(25(OH)D)levels and metabolic syndrome(MS)、MS components in patients with type2 diabetes mellitus;Methods: A total of 1045 patients with type 2 diabetes mellitus admitted to the First Affiliated Hospital of Xinjiang Medical University from January2018 to January 2019 were enrolled.The patients were divided into MS group(744 cases)and non-MS group(301 cases).Patients were divided into a sufficient group(170patients),a deficit group(559 patients),and a deficiency group(316 patients)according to serum 25(OH)D levels.Multivariate logistic regression was used to analyze the relationship between serum vitamin D levels and MS;Results: Height,weight,BMI,waist circumference,hip circumference,systolic blood pressure,diastolic blood pressure,TG in the MS group were significantly higher than those in the non-MS group(P<0.05).HDL-C,25(OH)D in MS group were significantly lower than those in non-MS group.There were significant differences in different serum 25(OH)D levels between the MS groups(P<0.05).The difference of 25(OH)D in different components of MS group was statistically significant(F=3.048,P<0.05).The 25(OH)D-sufficient group as a control logistic regression showed that the risk ratio(OR)of MS in the25(OH)D-deficient group and 25(OH)D-deficient group was 1.842 and 2.302,respectively(P<0.05);Conclusions: Decreased 25(OH)D levels may increase the risk of MS in patients with type 2 diabetes.