Correlation Between NLR,PLR And LMR In Preoperative Peripheral Blood And Prognosis Of Patients With Early Cervical Cancer

Objective:To investigate the peripheral blood neutrophil/lymphocyte ratio(NLR),platelet to lymphocyte ratio(PLR),and lymphatic/monocytes(LMR)in patients undergoing radical cervical cancer surgery.Methods:Analyze the relevant data of 116 patients diagnosed with cervical cancer(stage I-IIa)and received early radical surgery from the first affiliated hospital of Xinjiang Medical University from 2012 to 2018,and calculate NLR,PLR,and LMR.Relevance of clinical data and its impact on prognosis.Results:Differences in age and mass size between the high and low NLR groups were statistically significant(P<0.05).Differences in age,lymph node metastasis,mass size,and vascular infiltration in the high and low PLR groups were statistically significant(P<0.05).The differences in age and vascular infiltration in the high and low LMR group were statistically significant(P<0.05).The 5-year survival rate(34.4%)of patients in the high NLR group was lower than that of the low NLR group(63.3%),the 5-year survival rate(45.6%)of patients in the high PLR group was lower than that of the low PLR group(55.8%),and the 5-year survival rate(57.6%)of patients in the high LMR group was higher than that in the low LMR group(37.6%),and the differences were statistically significant(P<0.05).Univariate analysis showed that infiltration depth ≥ 1/2,NLR ≥ 2.77,PLR ≥ 133.57,LMR <4.04,clinical stage II,and lymph node metastasis are risk factors that affect the survival of patients.Multivariate analysis showed that NLR≥2.77,depth of infiltration≥1/2,and clinical stage II were independent risk factors that affected the survival rate of patients.Conclusion:Preoperative high NLR,high PLR and low LMR in cervical cancer patients are indicators of poor prognosis,NLR is more meaningful in predicting prognosis than the other two ratios.